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63-89-8

Name: L-alpha-Dipalmitoyl phosphatidylcholine

CAS: 63-89-8

Molecular Formula: C40H80NO8P

Molecular Weight: 734.039

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63-89-8 - Names and Identifiers

NameL-alpha-Dipalmitoyl phosphatidylcholine
Synonyms1,2-Dipalmitoyl-sn-glycero-3-phosphocholine monohydrate
L-A-phosphatidylcholine dipalmitoyl*synthetic
colfosceril palmitate
1,2-dipalmitoyl-3-sn-phosphatidylcholine
1,2-dipalmitoyl-L-alpha-phosphatidylcholine
L-a-Lecitin-dipalmitoyl
L-a-Dipalmitoyl Lecithin
(2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
CAS63-89-8
EINECS200-567-6
InChIInChI=1/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1
InChIKeyKILNVBDSWZSGLL-KXQOOQHDSA-N

63-89-8 - Physico-chemical Properties

Molecular FormulaC40H80NO8P
Molar Mass734.039
Melting Point229-229.5 °C
AppearanceForm Solid, color White to Off-White
Storage Condition-20°C
StabilityStable. Incompatible with strong oxidizing agents.
Physical and Chemical PropertiesChemical properties Monohydrate: Crystallization from thermal diisobutanone. Softened at 75~79 ℃. [α]D23 6.6. (C = 4.2,1:1 chloroform-methanol). Easily soluble in chloroform, hot diisobutanone or hot dioxane. Easily emulsified in water. Solubility at 22-23 ℃ (g/100ml): ethanol 1.5, ether 0.02, acetone 0.02, pyridine 1.1, acetic acid 4.0, methanol 1.4.
UseThe application is natural surface active substance, which is the main component of exogenous surface active substance preparation. It is used to rescue newborns with a birth weight of 700g or more who are mechanically ventilated for RDS.

63-89-8 - Risk and Safety

Safety Description24/25 - Avoid contact with skin and eyes.
WGK Germany3
FLUKA BRAND F CODES10-21
HS Code29232000

63-89-8 - Upstream Downstream Industry

Raw MaterialsTYLOXAPOL
Hexadecanoic acid, 1,1'-[1-[[(2-oxido-1,3,2-dioxaphospholan-2-yl)oxy]methyl]-1,2-ethanediyl] ester
[S,(+)]-1-O,2-O-Dipalmitoyl-3-O-trityl-L-glycerol
2-CHLOROETHYLPHOSPHORIC ACID DICHLORIDE
Choline glycerophosphate
1,2-DIPALMITOYL-SN-GLYCEROL
Choline tosylate
Palmitic acid
Trimethylamine

63-89-8 - Nature

specific rotation D23 6.6° (c = 4.2 in 1:1 chloroform-methanol)
Solubility Chloroform (Slightly), Methanol (Slightly)
Last Update:2022-08-11 19:27:49

63-89-8 - Uses and synthesis methods

biological activity

DPPC (129Y83) is a phosphoglyceride that can be used to prepare liposome monolayers. DPPC-liposome can be effectively used as a delivery vehicle for the induction of immune responses against GSL antigens in mice.

Target

Human Endogenous Metabolite

Production method

Synthetic surfactant, composed of palmitchphos plus decane alcohol and telosapor (Tyloxapo1).

Last Update:2022-08-11 19:27:49
L-alpha-Dipalmitoyl phosphatidylcholine suppliers
Suzhou Highfine Biotech Co., Ltd.
Product Name: 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
CAS : 63-89-8
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Suzhou Highfine Biotech Co., Ltd.
Product Name: 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
CAS : 63-89-8
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Fine Chem Trading LTD
Product Name: Colfosceril Palmitate
CAS : 63-89-8
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The Apotex Group
Product Name: 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
CAS : 63-89-8
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Chromafora
Product Name: L-alpha-Dipalmitoyl phosphatidylcholine
CAS : 63-89-8
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View History
63-89-8
Raw Materials for 63-89-8
TYLOXAPOL
Hexadecanoic
acid,
1,1'-[1-[[(2-oxido-1,3,2-dioxaphospholan-2-yl)oxy]methyl]-1,2-ethanediyl]
ester
[S,(+)]-1-O,2-O-Dipalmitoyl-3-O-trityl-L-glycerol
2-CHLOROETHYLPHOSPHORIC
ACID
DICHLORIDE
Choline
glycerophosphate
1,2-DIPALMITOYL-SN-GLYCEROL
Choline
tosylate
Palmitic
acid
Trimethylamine
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