Name | L-alpha-Dipalmitoyl phosphatidylcholine |
Synonyms | 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine monohydrate L-A-phosphatidylcholine dipalmitoyl*synthetic colfosceril palmitate 1,2-dipalmitoyl-3-sn-phosphatidylcholine 1,2-dipalmitoyl-L-alpha-phosphatidylcholine L-a-Lecitin-dipalmitoyl L-a-Dipalmitoyl Lecithin (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine |
CAS | 63-89-8 |
EINECS | 200-567-6 |
InChI | InChI=1/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1 |
InChIKey | KILNVBDSWZSGLL-KXQOOQHDSA-N |
Molecular Formula | C40H80NO8P |
Molar Mass | 734.039 |
Melting Point | 229-229.5 °C |
Appearance | Form Solid, color White to Off-White |
Storage Condition | -20°C |
Stability | Stable. Incompatible with strong oxidizing agents. |
Physical and Chemical Properties | Chemical properties Monohydrate: Crystallization from thermal diisobutanone. Softened at 75~79 ℃. [α]D23 6.6. (C = 4.2,1:1 chloroform-methanol). Easily soluble in chloroform, hot diisobutanone or hot dioxane. Easily emulsified in water. Solubility at 22-23 ℃ (g/100ml): ethanol 1.5, ether 0.02, acetone 0.02, pyridine 1.1, acetic acid 4.0, methanol 1.4. |
Use | The application is natural surface active substance, which is the main component of exogenous surface active substance preparation. It is used to rescue newborns with a birth weight of 700g or more who are mechanically ventilated for RDS. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10-21 |
HS Code | 29232000 |
specific rotation | D23 6.6° (c = 4.2 in 1:1 chloroform-methanol) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
biological activity
DPPC (129Y83) is a phosphoglyceride that can be used to prepare liposome monolayers. DPPC-liposome can be effectively used as a delivery vehicle for the induction of immune responses against GSL antigens in mice.
Target
Human Endogenous Metabolite
Production method
Synthetic surfactant, composed of palmitchphos plus decane alcohol and telosapor (Tyloxapo1).