Name | N-Hydroxy succinimide |
Synonyms | NHS HOSu HONSU NHS OR HONSU N-HYDROXYSUCCINIMDE 1-Hydroxysuccinimide N-HYDROXYSUCCINIMIDE N-Hydroxysuccinimide N-Hydroxy succinimide NHS N-HYDROXYSUCCINIMIDE, N-Hydroxysuccinimide (HOSu) 1-hydroxy-5-pyrrolidinedione 5-Pyrrolidinedione,1-hydroxy-2 N-HYDROXY-2,5-PYRROLIDINEDIONE 1-hydroxypyrrolidine-2,5-dione 1-Hydroxy-2,5-pyrrolidinedione 1-Hydroxy-2,5-pyrrolidine-dione N-HYDROXYSUCCINIMIDE POLYMER-BOUND N-Hydroxysuccinimide POLYMER-BOUND HOSu~1-Hydroxy-2,5-pyrrolidinedione |
CAS | 6066-82-6 |
EINECS | 228-001-3 |
InChI | InChI=1/C4H5NO3/c6-3-1-2-4(7)5(3)8/h8H,1-2H2 |
InChIKey | NQTADLQHYWFPDB-UHFFFAOYSA-N |
Molecular Formula | C4H5NO3 |
Molar Mass | 115.09 |
Density | 1.4769 (rough estimate) |
Melting Point | 95-98°C(lit.) |
Boling Point | 215.33°C (rough estimate) |
Flash Point | 112.5°C |
Water Solubility | SOLUBLE |
Solubility | Soluble in water (50 mg/ml), DMSO (100 mM), methanol, acetone (50 mg/ml), and DMF. |
Vapor Presure | 0Pa at 25℃ |
Appearance | White crystal |
Color | Clear yellow-brown to brown |
BRN | 113913 |
pKa | 7.81±0.20(Predicted) |
PH | 5-7 (50g/l, H2O, 20℃) |
Storage Condition | Store at +2°C to +8°C. |
Stability | Stable. Incompatible with strong oxidizing agents, acid chlorides, acid anhydrides, strong bases. Protect from moisture. |
Sensitive | Hygroscopic |
Refractive Index | 1.4080 (estimate) |
MDL | MFCD00005516 |
Physical and Chemical Properties | Appearance: white to off-white crystals; Melting point range: 95.0 ℃ ~ 98.0 ℃; |
Use | For the synthesis of amino acid protectants, semi-synthetic kanamycin and pharmaceutical intermediates. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
TSCA | Yes |
HS Code | 29251995 |
Hazard Note | Irritant |
Raw Materials | Succinic anhydride Hydroxylamine hydrochloride |