6-Quinolinecarboxylic acid, 2-methyl-, ethyl ester

6-Quinolinecarboxylic acid, 2-methyl-, ethyl ester - Names and Identifiers

Name	Ethyl 2-methylquinoline-6-carboxylate
Synonyms	ethyl2-methylquinoline-6-carboxylate Ethyl 2-Methyl-6-quinolinecarboxylate Ethyl 2-methylquinoline-6-carboxylate ethyl4-hydroxy-2-methylquinoline-6-carboxylate 2-Methylquinoline-6-carboxylic acid ethyl ester 2-Methyl-6-quinolinecarboxylic acid ethyl ester 6-quinolinecarboxylic acid, 2-methyl-, ethyl ester 6-Quinolinecarboxylic acid, 2-methyl-, ethyl ester
CAS	855763-77-8
InChI	InChI=1/C13H13NO2/c1-3-16-13(15)11-6-7-12-10(8-11)5-4-9(2)14-12/h4-8H,3H2,1-2H3

6-Quinolinecarboxylic acid, 2-methyl-, ethyl ester - Physico-chemical Properties

Molecular Formula	C13H13NO2
Molar Mass	215.25
Density	1.148±0.06 g/cm3(Predicted)
Boling Point	334.4±22.0 °C(Predicted)
Flash Point	156.1°C
Vapor Presure	0.000128mmHg at 25°C
Appearance	Solid
pKa	4.95±0.43(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.591

6-Quinolinecarboxylic acid, 2-methyl-, ethyl ester - Introduction

Ethyl is an organic compound with the chemical formula C13H13NO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Ethyl is a colorless to pale yellow liquid.
-Solubility: It is soluble in organic solvents such as ethanol, dimethylformamide and dichloromethane, and insoluble in water.
-Melting point and boiling point: Its melting point is -31°C and boiling point is 255°C.
-Stability: It is stable at room temperature and relatively stable to air and light.

Use:
- Ethyl has extensive research and application value in the field of medicine. It can be used as an intermediate in the synthesis of biologically active molecules, such as amino acid derivatives, organic heterocyclic compounds, etc. It can also be used as a precursor compound for the synthesis of anti-inflammatory drugs, anti-cancer drugs, antibiotics, etc.
-In addition, it can also be used as a reagent and catalyst in organic synthesis to synthesize complex organic compounds.

Preparation Method:
- Ethyl is usually prepared by reacting 2-methylquinoline and ethyl chloroacetate under alkaline conditions. In the course of the reaction, 2-methylquinoline-6-formate sodium salt is formed, which is subsequently neutralized and exchanged with an acid to form the desired product.

Safety Information:
-Wear appropriate personal protective equipment, including chemical protective gloves and goggles.
-Avoid contact with skin, eyes and respiratory tract. In case of contact, immediately flush the affected area with plenty of water and seek medical help.
-Keep containers sealed during storage and handling to avoid contact with oxidants and high heat sources.
-Observe relevant safety standards and guidelines when using and storing.

Last Update：2024-04-09 20:52:54