6-Isopropoxypyridin-3-boronic acid
(6-Isopropoxypyridin-3-yl)boronic acid
CAS: 870521-30-5
Molecular Formula: C8H12BNO3
6-Isopropoxypyridin-3-boronic acid - Names and Identifiers
6-Isopropoxypyridin-3-boronic acid - Physico-chemical Properties
| Molecular Formula | C8H12BNO3 |
| Molar Mass | 181 |
| Density | 1.16 |
| Boling Point | 325.5±52.0 °C(Predicted) |
| Flash Point | 150.656 °C |
| Water Solubility | Slightly soluble in water. |
| Appearance | Solid |
| pKa | 7.08±0.18(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
6-Isopropoxypyridin-3-boronic acid - Introduction
(6-Isopropoxypyridin-3-yl)boronic acid, also known as (6-isopropoxypyridin-3-yl) boronic acid, is an organoboron compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless or yellowish solid.
-Molecular formula: C10H15BNO3
-Molecular weight: 209.04g/mol
-melting point: about 150-152 ℃
-Solubility: Soluble in many organic solvents, such as methanol, ethanol and dichloromethane.
Use:
- (6-Isopropoxypyridin-3-yl)boronic acid is an important organic synthesis intermediate. It is widely used in C- N, C- O and C- C bond forming reactions, such as Suzuki-Miyaura cross coupling reaction, Stille reaction and Negishi reaction.
-It can be used to synthesize biologically active molecules, such as drugs and pesticides.
-can also be used as a coordination reagent and catalyst.
Preparation Method:
(6-Isopropoxypyridin-3-yl) The preparation method of boronic acid can be carried out by the following steps:
1.6-isopropoxy pyridine and boric acid reaction, in the appropriate solvent heating reaction.
2. After the reaction, the product is obtained by crystallization or solvent evaporation.
Safety Information:
- (6-Isopropoxypyridin-3-yl)boronic acid is a relatively safe compound under the conditions of correct use and storage.
-Avoid direct contact with skin and eyes during operation.
-When in use, use appropriate personal protective equipment, such as laboratory gloves and safety goggles.
-Further safety information and handling methods should refer to the safety data sheet of the compound.
Nature:
-Appearance: Colorless or yellowish solid.
-Molecular formula: C10H15BNO3
-Molecular weight: 209.04g/mol
-melting point: about 150-152 ℃
-Solubility: Soluble in many organic solvents, such as methanol, ethanol and dichloromethane.
Use:
- (6-Isopropoxypyridin-3-yl)boronic acid is an important organic synthesis intermediate. It is widely used in C- N, C- O and C- C bond forming reactions, such as Suzuki-Miyaura cross coupling reaction, Stille reaction and Negishi reaction.
-It can be used to synthesize biologically active molecules, such as drugs and pesticides.
-can also be used as a coordination reagent and catalyst.
Preparation Method:
(6-Isopropoxypyridin-3-yl) The preparation method of boronic acid can be carried out by the following steps:
1.6-isopropoxy pyridine and boric acid reaction, in the appropriate solvent heating reaction.
2. After the reaction, the product is obtained by crystallization or solvent evaporation.
Safety Information:
- (6-Isopropoxypyridin-3-yl)boronic acid is a relatively safe compound under the conditions of correct use and storage.
-Avoid direct contact with skin and eyes during operation.
-When in use, use appropriate personal protective equipment, such as laboratory gloves and safety goggles.
-Further safety information and handling methods should refer to the safety data sheet of the compound.
Last Update：2024-04-09 02:00:48
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View History
6-Isopropoxypyridin-3-boronic acid
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6-broMo-2,3-diMethyliMidazo[1,2-a]pyriMidine
3-fluoro-4-methoxyphenylacetic acid
5-(4,4,5,5-四甲基-1,3,2-二杂氧戊硼烷-2-基)-1H-吲哚-1-甲酸叔丁酯
549542-87-2
295344-96-6
2-ThiazoleethanaMine, dihydrochloride
72968-80-0
Benzo[b]thiophene-2-carboxamide, 3-chloro-N-ethyl-N-(2-methylphenyl)-
1H-Pyrazole-5-carboxamide, N-[(1S)-1-cycloheptyl-2-[[4-[(2R)-3-(4-methyl-1-piperazinyl)-3-oxo-2-[(1-oxopropyl)amino]propyl]phenyl]amino]-2-oxoethyl]-1-methyl-
6-broMo-2,3-diMethyliMidazo[1,2-a]pyriMidine