6-FLUOROINDOLE FOR SYNTHESIS 25 G
6-Fluoroindole
CAS: 399-51-9
Molecular Formula: C8H6FN
6-FLUOROINDOLE FOR SYNTHESIS 25 G - Names and Identifiers
| Name | 6-Fluoroindole |
| Synonyms | 6-FL uoroindoL 6-Fluoroindole 5-fluoro-1H-indole 6-Fluoro-1H-indole 6-FLUORO-2-IODOBENZALDEHYDE 6-FLUOROINDOLE FOR SYNTHESIS 5 G 6-Fluoroindole,6-Fluoro-1H-indole 6-FLUOROINDOLE FOR SYNTHESIS 25 G 6-Fluoroindole in stock Factory |
| CAS | 399-51-9 |
| EINECS | 700-113-1 |
| InChI | InChI=1/C8H6FN/c9-7-2-1-6-3-4-10-8(6)5-7/h1-5,10H |
6-FLUOROINDOLE FOR SYNTHESIS 25 G - Physico-chemical Properties
| Molecular Formula | C8H6FN |
| Molar Mass | 135.14 |
| Density | 1.1203 (estimate) |
| Melting Point | 72-76 °C (lit.) |
| Boling Point | 230°C (rough estimate) |
| Flash Point | 109.9°C |
| Water Solubility | Insoluble |
| Vapor Presure | 0.0226mmHg at 25°C |
| Appearance | Yellow crystal |
| Color | Beige-brown |
| BRN | 112192 |
| pKa | 16.40±0.30(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Light Sensitive |
| Refractive Index | 1.646 |
| MDL | MFCD00056933 |
| Physical and Chemical Properties | Melting Point 72-77°C water-soluble insoluble |
6-FLUOROINDOLE FOR SYNTHESIS 25 G - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection |
| WGK Germany | 3 |
| FLUKA BRAND F CODES | 10 |
| HS Code | 29339900 |
| Hazard Class | IRRITANT |
6-FLUOROINDOLE FOR SYNTHESIS 25 G - Reference Information
| use | 6-fluoroindole is an important variety of indole series products. it is an intermediate of antipsychotic drugs. there are many existing synthesis methods. some methods use difficult raw materials and high cost, and some methods use raw materials with high toxicity, some methods use the solvent smell is strong, easy to volatilize, not conducive to environmental protection, so the above methods are only in the laboratory stage, can not be used for large-scale industrial production. 6-fluoroindole can be widely used in the field of medicine and chemical industry, such as the preparation of 6-fluoroindole -3-acetonitrile. |
| application | 6-fluoroindole can be widely used in the field of medicine and chemical industry, such as the preparation of 6-fluoroindole -3-acetonitrile. 6-Fluoroindole-3-acetonitrile is a commonly used pharmaceutical intermediate. The first step of the preparation method is to synthesize 6-fluoroindole: the raw materials 6-fluoroindole, dimethylamine hydrochloride and paraformaldehyde are mixed in a molar ratio of 1:1~1.5: 1~2, and then added to the organic solvent After mixing evenly, it is continuously stirred during the reaction process, and it is heated and refluxed to prepare 6-fluoroindole-3-acetonitrile for later use; the second step is to synthesize 6-fluoroindole-3-acetonitrile: using the first step of the raw materials to prepare 6-fluoroindoleine and sodium cyanide according to the molar ratio of 1: 1~2 ingredients, the raw materials are mixed into an organic solvent, reflux reaction after the evaporation of the solvent, the extraction of the organic layer to 6-fluoroindole -3-acetonitrile. The synthesis route is short and can be completed in only two steps. The raw materials are easily available, the 3-position indole replacement is accurate, the control is convenient and the cost is low, the reaction yield is high, and the high-purity drug intermediate products are prepared, which are suitable for industrial production. |
Last Update：2024-04-09 21:54:55
Supplier List
Featured Products
Product Name: 6-Fluoroindole Request for quotationCAS: 399-51-9
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
Spot supply
Product Name: 6-Fluoroindole Request for quotationCAS: 399-51-9
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148
Wechat: 18162425036
Product Name: 6-Fluoroindole Request for quotation
CAS: 399-51-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 399-51-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 6-Fluoroindole Request for quotationCAS: 399-51-9
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: 6-Fluoroindole Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 6-FLUOROINDOLE Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 6-Fluoroindole Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 6-Fluoroindole Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 6-Fluoroindole Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: 6-Fluoroindole Request for quotation
CAS: 399-51-9
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
WhatsApp: 13605431940
CAS: 399-51-9
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
WhatsApp: 13605431940
Featured Products
Product Name: 6-Fluoroindole Request for quotationCAS: 399-51-9
Tel: +86-21-56795779
Email: charles7788@worldyachem.com
Mobile: +86-13651600618
QQ: 2850607228
Wechat: +8613651600618
WhatsApp: +8613651600618
Spot supply
Product Name: 6-Fluoroindole Request for quotationCAS: 399-51-9
Tel: +86-18162425036
Email: 3866263148@qq.com
Mobile: 18162425036
QQ: 3866263148
Wechat: 18162425036
Product Name: 6-Fluoroindole Request for quotation
CAS: 399-51-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
CAS: 399-51-9
Tel: 17505222756
Email: pules.cn@gmail.com
Mobile: +86-17551318830
Spot supply
Product Name: 6-Fluoroindole Request for quotationCAS: 399-51-9
Tel: +86-18721521379
Email: 18721521379@163.com
Mobile: +86-18721521379
Wechat: 18721521379
Spot supply
Product Name: 6-Fluoroindole Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: 6-FLUOROINDOLE Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 6-Fluoroindole Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 6-Fluoroindole Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 6-Fluoroindole Visit Supplier Webpage Request for quotationCAS: 399-51-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Product Name: 6-Fluoroindole Request for quotation
CAS: 399-51-9
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
WhatsApp: 13605431940
CAS: 399-51-9
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987
WhatsApp: 13605431940
View History
6-FLUOROINDOLE FOR SYNTHESIS 25 G
2-(2-甲基丙氧基)苯甲酸
3-Fluorobenzoic hydrazide 97%
(1S,4R,6S)-Tert-Butyl 6-Hydroxy-2-Azabicyclo[2.2.1]Heptane-2-Carboxylate
依来铬黑PV
Kunitz型丝氨酸肽酶抑制剂2
ETHANESULFONAMIDE
[2-HYDROXY-2-(4-NITRO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
2,2-Dimethyl-3-piperazin-1-yl-propionic acid methyl ester dihydrochloride
Α-D-GLUCOPYRANOSYL FLUORIDEΑ-D-氟代吡喃葡萄糖
2-(2-甲基丙氧基)苯甲酸
3-Fluorobenzoic hydrazide 97%
(1S,4R,6S)-Tert-Butyl 6-Hydroxy-2-Azabicyclo[2.2.1]Heptane-2-Carboxylate
依来铬黑PV
Kunitz型丝氨酸肽酶抑制剂2
ETHANESULFONAMIDE
[2-HYDROXY-2-(4-NITRO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
2,2-Dimethyl-3-piperazin-1-yl-propionic acid methyl ester dihydrochloride
Α-D-GLUCOPYRANOSYL FLUORIDEΑ-D-氟代吡喃葡萄糖