Name | benzobarbital |
Synonyms | benzonal Benzonal Benzobarbita benzoyluminal benzobarbital benzoylluminal Benzoyl luminal benzoylphenobarbital Benzoyl phenobarbital Benzoyl phenobarbitone 1-benzoyl-5-ethyl-5-phenyl-barbituricaci 1-benzoyl-5-ethyl-5-phenylbarbituricacid 1-benzoyl-5-ethyl-5-phenyl-barbituricacid 6(1h,3h,5h)-pyrimidinetrione,1-benzoyl-5-ethyl-5-phenyl-4 1-benzoyl-5-ethyl-5-phenyl-2,4,6-trioxohexahydropyrimidine 1-benzoyl-5-ethyl-5-phenylpyrimidine-2,4,6(1H,3H,5H)-trione 6(1h,3h,5h)-pyrimidinetrione,1-benzoyl-5-ethyl-5-phenyl-2,4 |
CAS | 744-80-9 |
EINECS | 1592732-453-0 |
InChI | InChI=1/C19H16N2O4/c1-2-19(14-11-7-4-8-12-14)16(23)20-18(25)21(17(19)24)15(22)13-9-5-3-6-10-13/h3-12H,2H2,1H3,(H,20,23,25) |
Molecular Formula | C19H16N2O4 |
Molar Mass | 336.34 |
Density | 1.3097 (rough estimate) |
Melting Point | 134.5°C |
Boling Point | 472.83°C (rough estimate) |
Appearance | Solid |
pKa | 6.41±0.10(Predicted) |
Refractive Index | 1.5700 (estimate) |
Physical and Chemical Properties | [Appearance] white crystalline powder, bitter taste [solubility] almost insoluble in water, 95% ethanol slightly soluble, ether dissolved, easily soluble in chloroform [melting point] 134-137 ℃ [clarity and color of solution] 5ml 1% 1N NaOH solution should be clear colorless [acidity] 6.0-6.8 [related impurities] phenobarbital ≤ 0.8% [diphenyl] derivative] ≤ 0.4%(TLC method) [Chloride] ≤ 0.005% [sulfate] ≤ 0.025% [sulfated ash] ≤ 0.1% [heavy metal] ≤ 0.001% [content] ≥ 99.0% |
Use | Antiepileptic drugs |
UN IDs | 3249 |
Hazard Class | 6.1(b) |
Packing Group | III |
Toxicity | dlt-mus-orl 20 mg/kg CYGEDX 10(2),1,76 |