Molecular Formula | C5H6N2OS |
Molar Mass | 142.18 |
Density | 1.291 (estimate) |
Melting Point | ~330°C (dec.)(lit.) |
Boling Point | 342.3°C at 760 mmHg |
Flash Point | 160.8°C |
Water Solubility | INSOLUBLE |
Solubility | Easily soluble in ammonia solution and sodium hydroxide solution, slightly soluble in alcohol, ether and acetone, very slightly soluble in water and ether, insoluble in benzene and chloroform |
Vapor Presure | 3.83E-05mmHg at 25°C |
Appearance | Solid |
Color | Clear colorless to yellow |
Merck | 14,6128 |
BRN | 115648 |
pKa | pKa 8.2 (Uncertain) |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Stability | Stability Incompatible with strong oxidizing agents, iodine, metals. |
Refractive Index | 1.6430 (estimate) |
MDL | MFCD00006040 |
Physical and Chemical Properties | White crystals. Decomposition at 326-331 °c. Soluble in ammonia solution and sodium hydroxide solution, slightly soluble in alcohol and acetone, very slightly soluble in water and ether, insoluble in benzene and chloroform. Saturated aqueous solution is neutral or slightly acidic to litmus. No smell, bitter, easy sublimation. |
Use | Intermediates of the cardiovascular drug dipyridamole. |
In vitro study | Methylthiouracil can reduce the formation of stored thyroid hormones, as well as thyroglobulin in the thyroid gland. Methylthiouracil is also used in conjunction with radioactive iodine. |
Risk Codes | R22 - Harmful if swallowed R40 - Limited evidence of a carcinogenic effect |
Safety Description | S36/37 - Wear suitable protective clothing and gloves. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
UN IDs | UN 3077 9 / PGIII |
WGK Germany | 3 |
RTECS | YR0875000 |
TSCA | Yes |
HS Code | 29335995 |
Hazard Note | Irritant/Possible Carcinogen |
Toxicity | MLD in rabbits (mg/kg): 2486 orally (Simon) |
Reference Show more | 1. Zhu, Zhenjun, et al. "Hypolipidemic effect of Youcha in hyperlipidemia rats induced by high-fat diet." Food & function 8.4 (2017): 1680-1687.https://doi.org/10.1039/C7FO00089H 2. Shan Shi, Ziying Liu, Zhengyuan Xue, Xiaohui Chen, Yang Chu,A plasma metabonomics study on the therapeutic effects of the Si-miao-yong-an decoction in hyperlipidemic rats,Journal of Ethnopharmacology,Volume 256,2020,112780,ISSN 0378-8741,https://doi 3. [IF=4.36] Shan Shi et al."A plasma metabonomics study on the therapeutic effects of the Si-miao-yong-an decoction in hyperlipidemic rats."J Ethnopharmacol. 2020 Jun;256:112780 |