Name | Protoporphyrin IX |
Synonyms | Protoporphyrin IX KAMMERER'S PORPHYRIN Kammerer's prophyrin PROTOPORPHYRINIX,FREEACID ProtoporphyrinIXpurplepowder PROTOPORPHYRIN-'IX', FOR FLUORESCENCE 2,18-Porphinedipropionic acid, 3,8,13,17-tetramethyl-7,12-divinyl- 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid 3,3-(3,7,12,17-tetramethyl-8,13-divinylporphine-2,18-diyl)di(propionic acid) 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl- 3,3'-(7,12-diethenyl-3,8,13,17-tetramethylporphyrin-2,18-diyl)dipropanoic acid |
CAS | 553-12-8 |
EINECS | 209-033-7 |
InChI | InChI=1/C34H34N4O4/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25/h7-8,13-16,35-36H,1-2,9-12H2,3-6H3,(H,39,40)(H,41,42)/b25-13u,26-13-,27-14-,28-15u,29-14u,30-15-,31-16u,32-16- |
InChIKey | FEDYMSUPMFCVOD-UJJXFSCMSA-N |
Molecular Formula | C34H34N4O4 |
Molar Mass | 562.66 |
Density | 1.1829 (rough estimate) |
Melting Point | >300 °C(Solv: acetone (67-64-1)) |
Boling Point | 629.06°C (rough estimate) |
Flash Point | 636.6°C |
Water Solubility | 106.9mg/L(25 ºC) |
Solubility | Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), chloroform, glacial acetic acid, alcohol |
Vapor Presure | 0mmHg at 25°C |
Appearance | Powder |
Color | purple |
Merck | 13,7990 |
BRN | 380795 |
Storage Condition | 2-8°C |
Stability | Light Sensitive |
Sensitive | light sensitive |
Refractive Index | 1.6000 (estimate) |
MDL | MFCD00151109 |
Use | Activation of soluble guanylate cyclase; fluorescent immunoprobe. Photosensitizer (photodynamic crosslinking). |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 8-10-23 |
Reference Show more | 1. Bai Dingding, Liao Xiaomeng, Liu Lijin, Tang Mengmeng, Xie Hongchen, Li An, Huang Yina. Effect of compound jujube powder on improving iron deficiency anemia in rats [J]. Food Science and Technology, 2019,44(04):94-98. 2. [IF = 5.316] Songmei Li et al."Enhanced electronic interaction in hemin @ Ni(OH)2 composite for efficient electronic catalyst evolution." J Alloy Compd. 2022 Feb;892:161780 |
NIST chemical information | information provided by: webbook.nist.gov (external link) |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
biological activity | Protoporphyrin IX is the final intermediate in the heme biosynthetic pathway. |
Use | protoporphyrin sodium is a liver function improving agent, which can promote cell tissue respiration, improve protein and glucose metabolism, anti-complement binding and other effects. Animal experiments show that the product can significantly reduce the role of aminotransferase and other enzymes in the liver injury caused by carbon tetrachloride activation of soluble guanosine acyl cyclase |