Name | chlorhexidine |
Synonyms | fimeil hexadol chlorhexidin chlorhexidine Chlor hexidine Chlorhexidine Base Chlorohexidine base chlorocyclohexatriene 1,6-bis(p-chlorophenyldiguanido)hexane 1,6-di(4'-chlorophenyldiguanido)hexane 1,6-bis(5-(p-chlorophenyl)biguandino)hexane 1,1'-hexamethylenebis(5-(p-chlorophenyl)-biguanid 5,5-bis(4-chlorophenyl)-1,1-hexamethylenedibiguanide 2,4,11,13-tetraazatetradecanediimidamide,n,n''-bis(4-chlorophenyl)-3,12-diim |
CAS | 55-56-1 |
EINECS | 200-238-7 |
InChI | InChI=1S/C22H30Cl2N10/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34) |
InChIKey | GHXZTYHSJHQHIJ-UHFFFAOYSA-N |
Molecular Formula | C22H30Cl2N10 |
Molar Mass | 505.45 |
Density | 1.1555 (rough estimate) |
Melting Point | 134-136 °C (lit.) |
Boling Point | 641.45°C (rough estimate) |
Flash Point | 27.987°C |
Water Solubility | 0.08 g/100 mL (20 ºC) |
Solubility | water: soluble0.08% at 20°C |
Vapor Presure | 13.402mmHg at 25°C |
Appearance | White powder |
Merck | 13,2108 |
BRN | 2826432 |
pKa | pKa 10.78 (Uncertain) |
Storage Condition | 2-8°C |
Stability | Stable. Incompatible with strong oxidizing agents. |
Refractive Index | 1.6300 (estimate) |
MDL | MFCD00009673 |
Physical and Chemical Properties | Melting Point: 132-136°C Boiling Point: 127.658°C at 760 mmHg flash point: 27.987°C water solubility: 0.08g/100 mL (20°C) |
Use | For the surface active form of fungicides, with a strong broad-spectrum antibacterial, bactericidal effect, gram-positive bacteria and negative bacteria are effective |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R43 - May cause sensitization by skin contact R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3077 9/PG 3 |
WGK Germany | 3 |
RTECS | DU1925000 |
FLUKA BRAND F CODES | 10-34 |
HS Code | 29215900 |
Hazard Class | 9 |
Packing Group | III |
Toxicity | LD50 orally in Rabbit: 5000 mg/kg |
Reference Show more | 1. Dong Sheng LIANG, LI Huanying LI, Xiao Hu XU, et al. Design, screening and evaluation of antimicrobial activity of polypeptides against Streptococcus mutans [J]. Journal of Southern Medical University, 2019, 39(7). 2. Feng, Xiao, et al. "Equilibrum solution, solvent effect and preferred solution of chlorhexidine in aquatic co-solvent solutions of (methanol, ethanol, N, N-dimethylformamide and 1, 4-dioxane)." The Journal of Chemical Thermodynamics 129 (2019): 148- |