[2-chroo-5-(trifluoromethyl)pyridin-3-yl]boronic acid is an organic compound with the chemical formula C6H4BClF3N.
Among them, there is a chlorine atom on the pyridine ring, and a trifluoromethyl group is combined with boronic acid. It is a solid compound with high chemical and thermal stability.
This compound has a wide range of applications in organic synthesis. It can be used as a ligand to coordinate with metal catalysts in cross-coupling reactions for the synthesis of organic molecules. In addition, in the pharmaceutical industry, it can also be used as an intermediate for the synthesis of drugs and pesticides.
The preparation of [2-chroo-5-(trifluoromethyl)pyridin-3-yl]boronic acid can be done by a variety of methods. One common method is by reacting an aromatic boronic acid with 2-chloro-5-trifluoromethylpyridine to produce the desired product. The reaction is usually carried out in a solvent under appropriate conditions, such as pH and temperature control.
Regarding safety information,[2-chloro-5-(trifluoromethyl)pyridin-3-yl]boronic acid may be irritating to eyes and skin. Therefore, it is necessary to avoid contact with eyes and skin when using, and wear appropriate protective measures when necessary. In addition, care should be taken to prevent inhalation and avoid accidental ingestion. It needs to be properly stored and handled before operation to ensure safe use.