5301-03-1 - Names and Identifiers
5301-03-1 - Physico-chemical Properties
Molecular Formula | C10H7BrN2O3
|
Molar Mass | 283.08 |
Density | 1.645±0.06 g/cm3(Predicted) |
Melting Point | 88 °C |
Boling Point | 428.1±40.0 °C(Predicted) |
pKa | -4.56±0.50(Predicted) |
5301-03-1 - Introduction
5-Bromomethyl-3-(3-nitrophenyl)-isoxazole is an organic compound whose chemical structure contains a nitro group, a bromomethyl group, and an isoxazole ring. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: 5-Bromomethyl-3-(3-nitrophenyl)-isoxazole is usually a yellow crystalline solid.
-Melting point: Its melting point is generally between 150-153°C.
-Solubility: It is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), dichloromethane, etc.
Use:
-Antibacterial activity: 5-Bromomethyl-3-(3-nitrophenyl)-isoxazole has antibacterial activity and has potential application value in the field of medicine.
-Chemical research: It can also be used as a raw material or intermediate in organic synthesis, and is widely used in chemical research.
Preparation Method:
The preparation method of 5-Bromomethyl-3-(3-nitrophenyl)-isoxazole is relatively complicated and can generally be synthesized by the following steps:
1.3-nitrobenzene boronic acid reacts with methylene magnesium bromide to generate 5-Bromomethyl-3-(3-nitrophenyl)-isoxazole-1-methylene benzene boronic acid.
2. The above product is reacted with N-bromomalonimide to generate 5-Bromomomethyl-3-(3-nitrophenyl)-isoxazole.
Safety Information:
-Since 5-Bromomethyl-3-(3-nitrophenyl)-isoxazole is a newly synthesized compound, its detailed safety information has not been fully determined.
-Care should be taken to follow appropriate laboratory safety practices when using or handling this compound, including wearing appropriate protective equipment (e. g., lab gloves, goggles, etc.).
-It should be stored in a dry, well-ventilated place, away from fire and combustibles.
Last Update:2024-04-09 21:04:16