519054-55-8 - Names and Identifiers
Name | 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran
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Synonyms | 2-(Benzofuran-5-yl) 2-dioxaborolan-2-yl)-1-benzofuran Benzofuran-5-boronic acid pinacol ester Benzo[b]furan-5-boronic acid, pinacol ester 2-(benzofuran-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan 2-(1-BenzofuraN-5-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[b]furan, 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran
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CAS | 519054-55-8
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InChI | InChI=1/C14H17BO3/c1-13(2)14(3,4)18-15(17-13)11-5-6-12-10(9-11)7-8-16-12/h5-9H,1-4H3 |
519054-55-8 - Physico-chemical Properties
Molecular Formula | C14H17BO3
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Molar Mass | 244.09 |
Density | 1.10±0.1 g/cm3(Predicted) |
Melting Point | 72 °C |
Boling Point | 340.0±15.0 °C(Predicted) |
Flash Point | 159.4°C |
Vapor Presure | 0.000174mmHg at 25°C |
Appearance | powder to crystal |
Color | White to Almost white |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
Refractive Index | 1.54 |
519054-55-8 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S37/39 - Wear suitable gloves and eye/face protection
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519054-55-8 - Introduction
5-(4,4, 5,5-tetrathyl-1, 3,2-dioxaborolan-2-yl)-1-benzofuran is an organic compound whose chemical formula is C17H17BO4. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran as white or off-white crystals.
-Melting point: about 144-149°C.
-Solubility: Soluble in common organic solvents (such as ethanol, ether and dimethylformamide).
Use:
-Laboratory research: 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran is commonly used as a reagent in organic synthesis.
-Organic synthesis: It can be used to synthesize other organic compounds, such as drugs and pesticides.
Preparation Method:
The preparation method of 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran involves the following steps:
1. First, benzofuran is dissolved in chloroform, and trifluoroacetic acid and trimethylamine are added at low temperature to produce the corresponding salt.
2. The resulting compound is then reacted with boric anhydride to produce 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran.
Safety Information:
- 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran is generally less toxic under normal conditions of use.
-However, as a chemical substance, it should comply with laboratory safety procedures, such as wearing appropriate personal protective equipment (such as laboratory gloves, goggles, and laboratory coats).
-At the same time, pay attention to avoid contact with strong oxidants or strong acids to avoid dangerous reactions.
-When handling 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzofuran, care should be taken to avoid inhaling its powder or touching the skin. If inhaled or touched, clean the affected area immediately and seek medical attention.
Last Update:2024-04-09 21:11:58