Name | Thidiazuron |
Synonyms | TDZ Thidiazuron N-phenyl-N-1,2,3,-thiadiazol-5-yluree N-Phenyl-N'-1,2,3-thiodiazol-5-yl urea 1-phenyl-3-(1,2,3-thiadiazol-5-yl)urea N-Phenyl-N'-(1,2,3-thiadiazol-5-yl)urea 5-Phenylcarbamoylamino-1,2,3-Thiadiazole THIDIAZURON PESTANAL (1-PHENYL- 3-(1,2,3 5-(N-Phenylcarbonylamino)-1,2,3-thiadiazole 1-PHENYL-3-(1,2,3-THIADIAZOL-5-YL)UREA*P LANT CELL C Thidiazauron (1-Phenyl-3-(1,2,3-thiadiazol-5-yl)-harnstoff |
CAS | 51707-55-2 |
EINECS | 257-356-7 |
InChI | InChI=1/C9H8N4OS/c14-9(12-8-6-10-13-15-8)11-7-4-2-1-3-5-7/h1-6H,(H2,11,12,14) |
InChIKey | HFCYZXMHUIHAQI-UHFFFAOYSA-N |
Molecular Formula | C9H8N4OS |
Molar Mass | 220.25 |
Density | 1.3493 (rough estimate) |
Melting Point | 213°C |
Boling Point | 1·51 |
Solubility | Soluble in dimethylformamide and dimethyl sulfoxide. |
Appearance | neat |
Merck | 13,9384 |
BRN | 1078092 |
pKa | 12.06±0.70(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.6390 (estimate) |
MDL | MFCD00078723 |
Physical and Chemical Properties | The pure product is a white odorless and tasteless crystalline solid. m.p.210 -212.5 °c (decomposition) (decomposition at 217 °c), vapor pressure 4 x 10-9Pa) (25 °c). Solubility at 25 ℃: dimethyl sulfoxide> 500g/L, dimethyl formamide> 500g/L, cyclohexanone 21.5g/L, acetone 8g/L, methanol 4.5g/L, ethyl acetate 0.8g/L, hexane 6mg/L, insoluble in aliphatic and aromatic hydrocarbons, solubility in water 31mg/L. Partition coefficient 59 (pH = 7.3). 200 deg C below the stability; Room temperature on the water stability, Half-Life> 24d; In the soil Half-Life <60d. |
Use | Used as plant growth regulator, suitable for cotton and other leaf removal |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R51/53 - Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. |
Safety Description | S22 - Do not breathe dust. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. |
UN IDs | UN 3077 9 / PGIII |
WGK Germany | 3 |
RTECS | YU1395000 |
Toxicity | LC50 (96-hour) for bluegill sun?sh, channel cat?sh and rainbow trout >1,000 mg/L (Hartley and Kidd, 1987); acute oral LD50 for rats >5,000 mg/kg (Hartley and Kidd, 1987), 5,350 mg/kg (RTECS, 1985). |
Reference Show more | 1. Shao Pei, Zhang Zhao, Wang Lin, et al. Effects of expander treatment on polyphenol content and antioxidant activity of kiwifruit [J]. Modern food science and technology, 2018(5). 2. Zhao Luzhou, Xin Fang, Sun Tianzun, et al. Physiological Analysis of overwintering bud development of Panax ginseng -- Analysis of endogenous plant hormones based on HPLC-MS/MS [J]. Journal of Northeast Normal University: natural science edition 2020(1):127-135. |
pure white, odorless, tasteless crystalline solid. The melting point was 217 °c (decomposition). The solubility at 25 ℃ is (g/L): dimethyl sulfoxide> 500, dimethyl formamide> 500, cyclohexanone 21.5, acetone 8, methanol 4.5, ethyl acetate 0.8, hexane 6, insoluble in aliphatic and aromatic hydrocarbons, solubility in water 31mg/L.
with diethyl carbonate as the starting material, thiazuron was prepared by hydrazine hydrolysis, addition, cyclization, amination and aminolysis.
urea plant growth regulators, mainly used as cotton defoliant, can also be used for apple trees, grapes and beans, soybeans, peanuts and other crops. Can also be used for the prevention and control of Humulus scandens, dog grass, Ma Tang, watching moniae, creeping grass, pig and other weeds.
rat oral LD50>4000mg/kg. Mouse oral LD50>5000mg/kg. Rabbit percutaneous LD50>4000mg/kg. Rats inhaled LC50> 2.3 mg/L(4H). Rats fed 2 years without the effect of the dose of 200mg/kg, dogs fed 1 year without the effect of the dose of lo0 mg/kg. No carcinogenic, teratogenic, mutagenic. Quail oral LD50>3160mg/kg. Rainbow trout LC50>lOOOmg/L( 96H), Daphnia LC50> 10 mg/L(48h). Non-toxic to bees.