Fmoc-R-3-Amino-3-(2-fluoro-phenyl)-propionic acid is an organic compound which is a fatty acid derivative containing an amino group and a carboxyl group, wherein R represents a varying functional group. Its chemical formula is C21H17FNO3.
Fmoc-R-3-amino -3-(2-fluorophenyl) propionic acid is mainly used as a synthetic reagent in chemical biology and pharmaceutical research. It can be used for the introduction and removal of protecting groups in peptide synthesis and solid phase synthesis. The compounds have important applications for determining the secondary structure of polypeptides and proteins. Due to its amino and carboxyl groups, it can react with other compounds in esterification, amidation, etc., thus playing a role in the change of biological activity.
The preparation method of Fmoc-R-3-amino -3-(2-fluorophenyl) propionic acid is complicated, and generally needs to be carried out by organic synthesis method. The specific preparation method will be different according to the structure and substituent of R.
When using Fmoc-R-3-amino -3-(2-fluorophenyl) propionic acid, it is necessary to pay attention to its safety. The compound may be irritating to the eyes, skin and respiratory tract, so contact must be avoided. Appropriate protective equipment such as gloves, goggles and face shields must be worn during operation. At the same time, it should be operated in a well-ventilated place to avoid inhaling its volatile products. If inhaled or exposed to the compound by accident, seek medical attention immediately and provide a safety data sheet.