5-chloro-N'-hydroxy-1H-indole-3-carboxamidine - Names and Identifiers
5-chloro-N'-hydroxy-1H-indole-3-carboxamidine - Physico-chemical Properties
Molecular Formula | C9H8ClN3O
|
Molar Mass | 209.63 |
Density | 1.57±0.1 g/cm3 (20 ºC 760 Torr) |
Boling Point | 429.9±48.0 °C(Predicted) |
Flash Point | 254°C |
Vapor Presure | 1.14E-10mmHg at 25°C |
pKa | 6.87±0.69(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.715 |
5-chloro-N'-hydroxy-1H-indole-3-carboxamidine - Introduction
5-choro-N '-hydroxy-1H-indole-3-carboxamidine is an organic compound with the formula C9H8ClN3O. The following is an introduction to its nature, use, formulation and safety information:
Nature:
5-choro-N'-hydroxy-1H-indole-3-carboxamidine is a solid compound with a yellow crystalline appearance. It has low solubility and is stable at certain temperatures. Its melting point is about 184-186 degrees Celsius.
Use:
5-chloro-N '-hydroxy-1H-indole-3-carboxamidine is commonly used as an antioxidant and anti-inflammatory agent. It has an inhibitory effect on a variety of cytokines, so it is used to study and treat related diseases, such as inflammatory bowel disease and autoimmune diseases.
Method:
The preparation of 5-chloro-N '-hydroxy-1H-indole-3-carboxamidine is generally accomplished by chemical synthesis. The specific process involves the reduction reaction of 5-chloroindole-3-carboxylic acid, and then converted to the corresponding formamidine compound by amidation reaction, and then the desired product is obtained by hydroxylation reaction.
Safety Information:
When using and handling 5-choro-N '-hydroxy-1H-indole-3-carboxamidine, you need to pay attention to the following safety precautions: It may be irritating to the eyes and skin, and direct contact needs to be avoided. During operation, care should be taken to use appropriate protective equipment, such as chemical gloves and goggles. In addition, you should avoid inhaling the dust or vapor of the solution, so it is best to use it in a well-ventilated environment. When storing, it needs to be kept in a dry, cool place and avoid contact with incompatible substances. Finally, the compound should be properly disposed of in accordance with local regulations.
Last Update:2024-04-10 22:29:15