5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione - Names and Identifiers
Name | 5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione
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Synonyms | 5-Fluorobarbituric acid 5-FluoropyriMidine-2,4,6-triol 5-Fluoropyrimidine-2,4,6(1H,3H,5H)-trione 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro- 5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-fluoro- (9CI)
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CAS | 767-80-6
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5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione - Physico-chemical Properties
Molecular Formula | C4H3FN2O3
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Molar Mass | 146.08 |
Density | 1.63±0.1 g/cm3 (20 ºC 760 Torr) |
Melting Point | 260℃ (dec.) (acetic acid ) |
pKa | 2.17±0.20(Predicted) |
Storage Condition | Room Temprature |
5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione - Introduction
5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione, also known as 5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White solid
-Molecular formula: C4H3FN2O3
-Molecular weight: 142.08g/mol
-Melting point: over 300 ℃
-Solubility: Soluble in water and some organic solvents
Use:
- 5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione is an important intermediate used in pharmaceutical and chemical research. It has a wide range of applications in pharmaceutical synthesis, organic synthesis and biochemistry.
-Due to its special structure, it plays an important role in the synthesis of nucleotide drugs and DNA repair enzyme inhibitors.
Preparation Method:
- 5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione There are many synthetic methods, the most common of which is to obtain 5-fluoropyrimidine by fluorination reaction of pyrimidine, and hydroxylation after subsequent reaction.
Safety Information:
The physical and chemical properties of -5-Fluoro-6-hydroxy-2,4(1H,3H)-pyrimidinedione have not been fully evaluated for their effects on humans, so appropriate laboratory and personal protective measures should be taken during use, storage and handling.
-Avoid contact with skin, eyes or respiratory tract during use, and operate in a well-ventilated environment.
-If ingestion or contact with the substance, seek medical attention immediately and bring the chemical's label or safety data sheet.
Last Update:2024-04-09 20:49:11