5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine - Names and Identifiers
Name | 5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine
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Synonyms | 2-HYDRAZINO-6-(TRIFLUOROMETHYL)PYRIDINE 2-hydrazinyl-6-(trifluoroMethyl)pyridine (6-Trifluoromethyl-pyridin-2-yl)-hydrazine Pyridine,2-hydrazinyl-6-(trifluoromethyl)- [6-(trifluoromethyl)-2-pyridinyl]hydrazine 5-(4-Fluorophenyl)-1,3,4-thiadiazol-2-amine 5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine 1,3,4-Thiadiazol-2-amine, 5-(4-fluorophenyl)-
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CAS | 94239-06-2 942-70-1
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InChI | InChI=1/C8H6FN3S/c9-6-3-1-5(2-4-6)7-11-12-8(10)13-7/h1-4H,(H2,10,12) |
5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine - Physico-chemical Properties
Molecular Formula | C6H6F3N3
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Molar Mass | 177.13 |
Density | 1.46±0.1 g/cm3(Predicted) |
Boling Point | 185.0±50.0 °C(Predicted) |
Flash Point | 166.6°C |
Vapor Presure | 3.98E-05mmHg at 25°C |
pKa | 9.17±0.70(Predicted) |
Refractive Index | 1.643 |
5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine - Risk and Safety
Hazard Symbols | T - Toxic
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5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine - Introduction
5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine is an organic compound whose molecular formula is C8H6FN3S. The following is a description of the properties, uses, preparation and safety information of this compound:
Nature:
-Appearance: White crystalline solid.
-Melting point: about 180-185 degrees Celsius.
-Stability: Stable at room temperature and pressure.
-Solubility: Soluble in some organic solvents such as dimethyl sulfoxide, dimethylformamide and acetonitrile.
Use:
- 5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine can be used as a pharmaceutical intermediate. Thiadiazoles have a wide range of applications in the field of medicine, such as antibacterial agents, anti-inflammatory agents, anti-tumor drugs and so on.
Method:
- 5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine can be synthesized by chemical synthesis methods. A common method is the reaction of 4-fluorobenzimide with thiourea under basic conditions to obtain the target product through tautomerization.
Safety Information:
The toxicity and risk of -5-(4-fluorophenyl)-1,3,4-thiadiazol-2-amine have not been fully assessed. During use, appropriate personal protective measures should be taken, such as wearing protective glasses, masks and gloves. At the same time, avoid inhaling, chewing or touching the skin, and maintain good ventilation conditions. If exposed or inhaled, seek medical advice immediately and bring the compound's safety data sheet with you.
Last Update:2024-04-09 21:11:58