5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine - Names and Identifiers
Name | 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine
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Synonyms | EOS-60712 -4-(trifluoromethyl) 2-Amino-4-Trifluoropyrimidine-5-Boronic Acid Pinacol Ester 2-AMINO-4-TRIFLUOROPYRIMIDINE-5-BORONIC ACID PINACOL ESTER 2-amino-4-thifluoropyrimidine-5-boronic acid pinacol ester 2-Amino-4-trifluoromethylpyrimidine-5-boronic acid pinacol ester 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine 2-Pyrimidinamine, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)- 5-(4,4,5,5-tetramethyl(1,3,2-dioxaborolan-2-yl))-4-(trifluoromethyl)pyrimidine-2-ylamine [5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-yl]amine
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CAS | 944401-58-5
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InChI | InChI=1S/C11H15BF3N3O2/c1-9(2)10(3,4)20-12(19-9)6-5-17-8(16)18-7(6)11(13,14)15/h5H,1-4H3,(H2,16,17,18) |
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine - Physico-chemical Properties
Molecular Formula | C11H15BF3N3O2
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Molar Mass | 289.06 |
Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine - Introduction
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine, chemical formula C10H11BF3N3O2, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
1. nature:
-Appearance: 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine as a white crystalline solid.
-Solubility: The compound can be dissolved in common solvents.
-Melting point: The melting point of the compound is about 86-87°C.
-Stability: It is relatively stable under conventional conditions, but should avoid contact with strong oxidants and strong acids.
2. use:
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine has a wide range of applications, including:
-As a drug intermediate: It is often used as an intermediate for the synthesis of chemical drugs, used in the manufacture of anti-cancer drugs, anti-infective agents, etc.
-As a pesticide intermediate: The compound can also be used to synthesize pesticide intermediates, used in the manufacture of pesticides, herbicides, etc.
3. preparation method:
5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine can be synthesized:
-By adding 4,4, 5,5-tetramethyl -1,3, 2-diazine boron dioxide, aminopyrimidine and trifluoromethanethiol in an appropriate solvent, and then reacting at an appropriate temperature, the target product is finally obtained.
4. Safety Information:
- 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-(trifluoromethyl)pyrimidin-2-amine are generally relatively safe under correct conditions of use and storage. However, it is still an organic compound, and the following matters need to be paid attention:
-Avoid prolonged skin contact to prevent allergies or irritation.
-Avoid inhaling its dust or vapor during use to avoid damage to the respiratory system.
-Take appropriate laboratory safety measures during use and handling, including wearing appropriate protective equipment and using ventilation equipment.
Last Update:2024-04-09 19:05:53