3-(3-Nitrophenyl)-5-aminopyrazole is an organic compound with the chemical formula C11H8N4O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-(3-nitrophenyl)-5-aminopyrazole is a white or light yellow crystalline powder.
-Melting point: about 215-218 degrees Celsius.
-Solubility: It has good solubility in commonly used organic solvents such as ethanol, dimethyl sulfoxide and dichloromethane.
Use:
- 3-(3-nitrophenyl)-5-aminopyrazole is commonly used as a dye intermediate and a starting material for organic synthesis.
-It can also be used as a synthetic intermediate for anti-tumor drugs.
Preparation Method:
- 3-(3-nitrophenyl)-5-aminopyrazole can be obtained by the reaction of nitric acid with 3-aminophenylpyrazole.
-The specific preparation method is as follows:
1. Dissolve 3-aminophenylpyrazole in nitric acid.
2. Stir the reaction mixture at low temperature.
3. Filter to obtain a precipitate, wash and dry the precipitated product.
Safety Information:
- 3-(3-nitrophenyl)-5-aminopyrazole is an organic compound with potential danger.
-Wear chemical protective gloves, safety glasses and protective mask during operation.
-Avoid inhalation, avoid contact with skin and eyes.
-In case of skin contact or inhalation, rinse immediately with plenty of water and seek medical attention.
-should be stored in a dry, ventilated place, avoid contact with combustibles, away from the source of fire.