5-(3-lodo-phenyl)-2H-pyrazol-3-ylamine is an organic compound whose chemical formula is C11H10IN3. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Solubility: Soluble in organic solvents such as ethanol and dimethyl sulfoxide
-Melting Point: 173-175°C
-Stability: stable at room temperature, but avoid exposure to sunlight
Use:
- 5-(3-lodo-phenyl)-2H-pyrazol-3-ylamine is an important pharmaceutical intermediate, commonly used in organic synthesis
-It can be used to prepare a series of biologically active compounds, such as drugs, dyes and pesticides
Preparation Method:
The synthesis of 5-(3-Iodo-phenyl)-2H-pyrazol-3-ylamine can be carried out by the following steps:
1. First, 3-iodobenzoic acid reacts with sodium hypocyanite to generate the corresponding 3-iodobenzonitrile compound.
2. Next, 3-iodobenzonitrile is reacted with hydrazine, and the reaction is heated in ethanol to produce the target compound 5-(3-Iodo-phenyl)-2H-pyrazol-3-amine.
Safety Information:
-Wear appropriate personal protective equipment during use, including eye and skin protection.
-Avoid direct inhalation of its dust or steam, to ensure that the operation in a well-ventilated place.
-Avoid contact with eyes, skin and clothing. If contact occurs, rinse immediately with water.
-Please store it in a closed container under cool, dry and ventilated conditions.