5-溴-3-(三氟甲基)吡啶甲酸

5-溴-3-(三氟甲基)吡啶甲酸 - Names and Identifiers

Name	5-Bromo-3-(trifluoromethyl)picolinic acid
Synonyms	5-Bromo-3-(trifluoromethyl)picolinic acid 5-BroMo-3-(trifluoroMethyl)picolinic acid 5-broMo-3-(trifluoroMethyl)pyridine-2-carboxylic acid 2-Pyridinecarboxylic acid, 5-bromo-3-(trifluoromethyl)-
CAS	1211580-84-5

5-溴-3-(三氟甲基)吡啶甲酸 - Physico-chemical Properties

Molecular Formula	C7H3BrF3NO2
Molar Mass	270
Density	1.863±0.06 g/cm3(Predicted)
Boling Point	288.0±40.0 °C(Predicted)
pKa	2.46±0.36(Predicted)
Storage Condition	2-8°C

5-溴-3-(三氟甲基)吡啶甲酸 - Introduction

5-Bromo-3-trifluoromethylpyridine-2-carboxylic acid is an organic compound with the chemical formula C8H5BrF3NO2.

Nature:
The compound is a white solid that is stable at room temperature. It is a combination of organic bromine compounds and trifluoromethyl compounds, and has high thermal and chemical stability. It is soluble in some organic solvents such as dimethylformamide and dichloromethane.

Use:
5-Bromo-3-trifluoromethylpyridine-2-carboxylic acid is mainly used as a catalyst in organic synthesis reactions. It can be used in the synthesis of carbon and nitrogen compounds, acylation reactions and other organic synthesis reactions in the fluorination reaction.

Preparation Method:
The preparation of 5-bromo-3-trifluoromethylpyridine-2-carboxylic acid can be obtained by reacting 3-trifluoromethylpyridine-2-carboxylic acid with bromine. In the reaction, bromine will replace one of the hydrogen atoms in 3-trifluoromethylpyridine-2-carboxylic acid to form the desired product.

Safety Information:
There are no detailed reports on the toxicity and safety of 5-bromo-3-trifluoromethylpyridine-2-carboxylic acid. However, since it is a combination of an organic bromine compound and a trifluoromethyl compound, in general, similar compounds need to be handled safely. Wear protective gloves, goggles and protective clothing during operation, avoid direct contact with skin and eyes, and avoid inhaling its vapor. Use should be carried out in a well-ventilated place to avoid the concentration of dangerous gases. At the same time to comply with the relevant laboratory safety practices.

Last Update：2024-04-10 22:29:15