5,7-Dibromo-1H-indazole - Names and Identifiers
Name | 5,7-Dibromo-1H-indazole
|
Synonyms | 5,7-DIBROMO-1H-INDAZOLE 5,7-Dibromo-1H-indazole 1H-indazole, 5,7-dibromo- 1H-Indazole, 5,7-dibromo- 5,7-dibromo-1(2)H-indazole
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CAS | 50477-28-6
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InChI | InChI=1/C7H4Br2N2/c8-5-1-4-3-10-11-7(4)6(9)2-5/h1-3H,(H,10,11) |
5,7-Dibromo-1H-indazole - Physico-chemical Properties
Molecular Formula | C7H4Br2N2
|
Molar Mass | 275.93 |
Density | 2.164±0.06 g/cm3(Predicted) |
Melting Point | 197-198 °C |
Boling Point | 384.6±22.0 °C(Predicted) |
Flash Point | 186.4°C |
Vapor Presure | 8.92E-06mmHg at 25°C |
pKa | 10.56±0.40(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.751 |
5,7-Dibromo-1H-indazole - Introduction
5,7-Dibromo-1H-indazole is an organic compound with a chemical formula of C7H4Br2N and a molecular weight of 266.93g/mol. The following is an introduction to some of its properties, uses, formulation and safety information:
Nature:
-Appearance: 5,7-Dibromo-1H-indazole is a white to light yellow solid.
-Melting point: Its melting point is 188-192°C.
-Solubility: It has good solubility in some organic solvents, such as dimethyl sulfoxide (DMSO) and chloroform (CHCl3).
Use:
5,7-Dibromo-1H-indazole has a wide range of applications, some of the main uses include the following:
-Drug research: It is often used as a drug intermediate for the synthesis of a variety of biologically active compounds, such as anti-cancer drugs and inhibitors.
-Chemical research: Due to its special structure and properties, it also has important applications in organic synthesis and catalytic reactions.
-Dye industry: as a raw material for dyes and pigments.
Preparation Method:
There are two main preparation methods for 5,7-Dibromo-1H-indazole:
-obtained by reaction of indazole with brominated sulfoxide (Br2SO). Under rapid stirring, the indazole and sulfoxide bromide are dissolved in a suitable solvent for reaction, and the target product can be obtained through appropriate post-treatment and purification process.
-Another method is prepared by three reactions of indazole with brominated sulfoxide (Br2SO) and phosphorus tribromide (PBr3) in a suitable solvent.
Safety Information:
There is no detailed research and report on the safety information of 5,7-Dibromo-1H-indazole. However, because it is an organic compound, general chemical safety practices still apply. When in use, it is recommended to wear chemical protective gloves and goggles to prevent direct contact with skin and eyes. In the process of storage and handling, please follow the corresponding safety operation guidelines and measures to ensure safe use.
Last Update:2024-04-10 22:41:03