5,5-dideuterio-5-(3,4,4-trideuteriodithiolan-3-yl)pentanoic acid - Names and Identifiers
5,5-dideuterio-5-(3,4,4-trideuteriodithiolan-3-yl)pentanoic acid - Physico-chemical Properties
Molecular Formula | C8H9D5O2S2
|
Molar Mass | 211.35636889 |
Melting Point | 52-53°C |
Solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Pale Yellow to Light Yellow |
Storage Condition | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
5,5-dideuterio-5-(3,4,4-trideuteriodithiolan-3-yl)pentanoic acid - Introduction
A rac α-Lipoic Acid-d5 (also known as an alphalipoic acid or ALA-d5) is a nuclear magnetic resonance (NMR) standard that is commonly used in fields such as pharmaceutical research, biochemical research, and new drug development.
its nature:
-chemical formula: C8H10O2S2D5
-Molecular weight: 206.35g/mol
-Appearance: White crystalline powder
-Melting point: 58-60 ° C
-Solubility: Dissolved in water, solubility increases with increasing temperature
Use:
- NMR standard: as a standard of known structure, used to determine the structure of other compounds in NMR spectrum analysis
-Metabolic research: In drug metabolism research, it can be used to track and quantify the metabolic pathways and metabolites of compounds
-Biological activity Research: As an antioxidant, it can be used to study its role in cell protection and anti-inflammatory biological activities
Method:
The preparation of rac α-Lipoic Acid-d5 is generally achieved by nucleotide ring opening reaction and reduction reaction. The specific method involves a series of organic synthesis reactions, including the use of diazonium salt or fluoride to replace the sulfur-sulfur double bond formed by sulfur redox reaction, and then the synthesis of acetophenone, the replacement of deuterium and other steps.
Safety Information:
rac α-Lipoic Acid-d5 is a chemical, so it is necessary to pay attention to safe operation. It is insoluble in organic solvents, but has high solubility in water, so care should be taken to prevent inhalation, skin contact and accidental ingestion. Wear protective gloves, goggles and anti-inhalation mask as necessary. During storage and handling, it should be kept in a dry, cool, dark place, and avoid contact with oxidants and strong acids. If necessary, refer to the Safety Data Sheet (MSDS) of the chemical for more detailed safety information. The compound is best used in a professional chemistry laboratory environment.
Last Update:2024-04-09 21:32:49