49834-62-0 - Names and Identifiers
Name | 1H-pyrazolo[3,4-b]pyridin-4-amine
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Synonyms | 112750 NSC 221097 1H-PYRAZOLO[3,4-B]PYRIDIN-4-AMINE 1H-pyrazolo[3,4-b]pyridin-4-amine 4-AMino-1H-pyrazolo[3,4-b]pyridin 4-AMino-1H-pyrazolo[3,4-b]pyridine
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CAS | 49834-62-0
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InChI | InChI=1/C6H6N4/c7-5-1-2-8-6-4(5)3-9-10-6/h1-3H,(H3,7,8,9,10) |
49834-62-0 - Physico-chemical Properties
Molecular Formula | C6H6N4
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Molar Mass | 134.14 |
Density | 1.61 |
Boling Point | 199℃ |
Flash Point | 74℃ |
Vapor Presure | 1.5E-07mmHg at 25°C |
pKa | 6.51±0.20(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.806 |
49834-62-0 - Introduction
1H-pyrazolo[3,4-b]pyridin-4-amine is an organic compound with the chemical formula C8H7N3. The following is a description of the relevant properties, uses, preparation and safety information of the compound:
Nature:
1H-pyrazolo[3,4-b]pyridin-4-amine is a colorless to pale yellow crystalline powder. It is soluble in organic solvents such as ethanol, dimethyl sulfoxide and dimethylformamide, but insoluble in water. The compound is stable in air but away from strong acids and bases.
Use:
1H-pyrazolo[3,4-b]pyridin-4-amine is an important organic synthesis intermediate. It can be used in the preparation of pyrazolo [3,4-b] pyridine compounds, which have a wide range of applications in the field of medicine, for example, as a raw material for antitumor drugs and antiviral drugs.
Preparation Method:
1H-pyrazolo[3,4-b]pyridin-4-amine has various preparation methods. the following is one of the commonly used synthetic routes: 1H-pyrazolo[3,4-b] pyridine-4-nitramine is first obtained by nitrification reaction, and then reduced to 1H-pyrazolo[3,4-b]pyridin-4-amine by reducing agent.
Safety Information:
1H-pyrazolo[3,4-b]pyridin-4-amine is a relatively safe compound under normal use and storage conditions. However, as a chemical, it still has certain safety risks. When in contact with this compound, avoid direct inhalation of its dust or vapor, and avoid skin contact and ingestion. When in use, wear chemical protective gloves and protective glasses to ensure adequate ventilation. If accidental contact or inhalation occurs, wash the area immediately and seek medical attention. When stored, it should be placed in a closed container, away from fire and oxidizing agents.
Last Update:2024-04-09 20:45:29