Methyl 2-(bromomethyl)-6-chroo-benzoate is an organic compound with the chemical formula C. H₂ BrClO₂. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless liquid or solid with special fragrance.
-Melting point: 43-45°C
-Boiling Point: 249-250°C
-Density: 1.63g/cm³
-Solubility: Soluble in organic solvents, such as ethanol, chloroform and dimethylformamide.
Use:
methyl 2-(bromomethyl)-6-chloroo-benzoate is often used as a raw material or intermediate in organic synthesis. Specific applications include:
-Drug synthesis: As an intermediate for the synthesis of certain drugs, it plays an important role in drug research and development.
-Pesticide Synthesis: Used to synthesize certain pesticides and herbicides.
-Chemical research: Reactions and reagents that can be used in organic research.
Preparation Method:
The preparation of methyl 2-(bromomethyl)-6-chloro-benzoate can be carried out by the following steps:
1.2-methyl -6-chlorobenzoic acid methyl ester and methyl bromide reaction.
2. after the start of the reaction into the dry hydrogen chloride gas.
3. Heat the reaction mixture, and separate and purify it to obtain pure methyl 2-(bromomethyl)-6-chloro-benzoate.
Safety Information:
- methyl 2-(bromomethyl)-6-chloroo-benzoate may be irritating to skin, eyes, and respiratory tract.
-Wear appropriate personal protective equipment such as gloves, goggles and gas masks when used.
-Avoid contact with skin, eyes and taking.
-Operate in a well-ventilated place and away from open flames and heat sources.
-Avoid direct sunlight during storage and store in a dry, cool place.