480439-47-2 - Names and Identifiers
480439-47-2 - Physico-chemical Properties
Molecular Formula | C8H17ClO2Si
|
Molar Mass | 208.76 |
Density | 1.001g/mLat 25°C(lit.) |
Boling Point | 48-49°C0.2mm Hg(lit.) |
Flash Point | 154°F |
Vapor Presure | 0.669mmHg at 25°C |
Refractive Index | n20/D 1.437(lit.) |
480439-47-2 - Risk and Safety
Hazard Symbols | C - Corrosive
|
Risk Codes | 34 - Causes burns
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
|
UN IDs | UN 3267 8/PG 2 |
WGK Germany | 3 |
480439-47-2 - Introduction
tert-butyl(dimethyl)silyl chloroacetate(tert-butyl(dimethyl)silyl chloroacetate) is an organic compound with the chemical formula C10H21ClO2Si. Its nature is as follows:
-Appearance: colorless liquid
-Solubility: Can be dissolved in common organic solvents, such as ether, acetone and dichloromethane.
tert-butyl(dimethyl)silyl chloroacetate has many uses in organic synthesis, such:
-As a protecting group: Due to its stability and easy removal properties, it can be used as a reagent to protect hydroxyl and amine groups in organic synthesis.
-Used to prepare acid and diazo reagent: It can be reacted with some acidic reagents (such as trifluoromethanesulfonic acid) to prepare the corresponding acid, or reacted with diazo compound to obtain imine.
Preparation of tert-butyl(dimethyl)silyl chloroacetate:
can usually be synthesized by the following methods:
Trimethylchlorosilane is reacted with tert-butyldimethyl azidoformate to generate tert-butyl(dimethyl)silyl chloroacetate.
About safety information:
tert-butyl(dimethyl)silyl chloroacetate is an organic compound, you need to pay attention to the following safety matters:
-During use, wear appropriate protective equipment, such as gloves and glasses.
-Avoid inhaling its vapor or dust and ensure that the operation is carried out under well-ventilated conditions.
-Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water and seek medical advice.
-When storing and carrying, keep away from combustible and oxidizing substances, and keep the container tightly closed to prevent leakage and volatilization.
Last Update:2024-04-10 22:29:15