478830-50-1 - Names and Identifiers
478830-50-1 - Physico-chemical Properties
Molecular Formula | C12H15N3O
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Molar Mass | 217.27 |
Boling Point |
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478830-50-1 - Introduction
1H-Indazole, 4-(3-piperidinyloxy)-is an organic compound with the chemical formula C12H14N4O. It is a white crystalline solid, stable at room temperature. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-Molecular weight: 226.27g/mol
-Melting point: 98-99°C
-Boiling point: 395.5°C
-relative density: 1.193g/cm³
-Solubility: Good solubility in organic solvents, such as methanol, dimethylformamide, etc.
Use:
- 1H-Indazole, 4-(3-piperidinyloxy)-has many uses, one of which is as an intermediate in organic synthesis. It can be used to synthesize other compounds, such as pesticides, pharmaceuticals and functional materials.
-It can also be used as a fluorescent dye and biomarker.
Preparation Method:
- 1H-Indazole, 4-(3-piperidinyloxy)-has different synthetic methods, but a common method is to prepare by reacting piperidine and chloroalkoxide. Specific steps include:
1. Under an inert atmosphere, piperidine and a base (such as potassium carbonate) are added to the solvent.
2. Add chloroalkoxide (such as chloromethanol).
3. Heat the reaction mixture and stir for a period of time.
4. Cool the reaction mixture and add an acidic aqueous solution.
5. The organic phase was separated and dried.
6. 1H-Indazole, 4-(3-piperidinyloxy)-was finally obtained by crystallization purification-.
Safety Information:
The safety of-1H-Indazole, 4-(3-piperidinyloxy)-has not been widely studied, so the relevant safety operation procedures should be followed when using and handling.
-Because it is an organic compound, it may be irritating, toxic or otherwise dangerous. Therefore, personal protective equipment such as laboratory gloves, protective glasses and laboratory coats should be used during use.
-At the same time, for any chemical use, it should be operated in a well-ventilated place, and follow the correct operating procedures and waste disposal methods.
Please note that this information is for reference only, and the specific experimental operation and use should be carried out according to actual needs and relevant safety regulations.
Last Update:2024-04-09 21:11:58