Name | 4-Nitroindole |
Synonyms | 4-Nitorindole 4-NITROINDOLE 4-Nitroindole 4-Nitro indole Nitroindole,4- 4-NITRO-1H-INDOLE 4-Nitro-1H-indole 1H-Indole, 4-nitro- 4-Nitroindole in stock Factory |
CAS | 4769-97-5 |
EINECS | 689-317-9 |
InChI | InChI=1/C8H6N2O2/c11-10(12)8-3-1-2-7-6(8)4-5-9-7/h1-5,9H |
InChIKey | LAVZKLJDKGRZJG-UHFFFAOYSA-N |
Molecular Formula | C8H6N2O2 |
Molar Mass | 162.15 |
Density | 1.3264 (rough estimate) |
Melting Point | 205-207 °C (lit.) |
Boling Point | 288.82°C (rough estimate) |
Flash Point | 173.1°C |
Solubility | Acetone, Dichloromethane, Ethyl Acetate, Methanol |
Vapor Presure | 3.98E-05mmHg at 25°C |
Appearance | Yellow powder |
Color | Yellow |
BRN | 136022 |
pKa | 14.76±0.30(Predicted) |
Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
Refractive Index | 1.5770 (estimate) |
MDL | MFCD00010056 |
Physical and Chemical Properties | Melting point 203-207°C |
Use | Used as a reagent for organic synthesis |
Risk Codes | 68 - Possible risk of irreversible effects |
Safety Description | S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. S24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
HS Code | 29339900 |
Hazard Note | Irritant |
Hazard Class | IRRITANT, IRRITANT-H |
Introduction | 4-nitroindole is an important intermediate for the preparation of other simple 4-indole, and it is also an important raw material for the synthesis of dyes and drugs. There are few domestic researches on the synthesis method of 4-nitroindole. At present, the commonly used methods include the synthesis of 4-nitroindole by 2-methyl-3-nitroaniline ring, and the cyclization of m-nitrophenylhydrazone. Hydrolysis to produce 4-nitroindole, 4-nitroindole from m-dinitrobenzene derivatives, 4-nitroindole from 4-nitroindole, etc. |
Use | Used as an organic synthesis reagent |