Name | Bufotaline |
Synonyms | BUFOTALIN Bufotalin Bufotaline BUFOTALIN SULFATE 16-(acetyloxy)-3,14-dihydroxybufa-20,22-dienolide 16-(Acetyloxy)-3,14-dihydroxybufa-20,22-dienolide 3b,14,16b-Trihydroxy-5b-bufa-20,22-dienolide 16-acetate 3-BETA-14,16-BETA-TRIHYDROXY-5BETA-BUFA-20,22-DIENOLIDE SULFATE 22-dienolide,3-beta,14,16-beta-trihydroxy-5-beta-bufa-216-acetate 5beta-Bufa-20,22-dienolide, 3beta,14,16beta-trihydroxy-, 16-acetate Bufa-20,22-dienolide, 16-(acetyloxy)-3,14-dihydroxy-, (3beta,5beta,16beta)- (3beta,5beta,8xi,9xi,16beta)-16-(acetyloxy)-3,14-dihydroxybufa-20,22-dienolide |
CAS | 471-95-4 |
InChI | InChI=1/C26H36O6/c1-15(27)32-21-13-26(30)20-6-5-17-12-18(28)8-10-24(17,2)19(20)9-11-25(26,3)23(21)16-4-7-22(29)31-14-16/h4,7,14,17-21,23,28,30H,5-6,8-13H2,1-3H3 |
Molecular Formula | C26H36O6 |
Molar Mass | 444.56 |
Density | 1.0942 (rough estimate) |
Melting Point | 223°C (rough estimate) |
Boling Point | 474.53°C (rough estimate) |
Specific Rotation(α) | D20 +5.4° (c = 0.5 in chloroform) |
Flash Point | 195.8°C |
Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents. |
Vapor Presure | 1.82E-16mmHg at 25°C |
Appearance | White powder |
pKa | 14.44±0.70(Predicted) |
Storage Condition | 2-8℃ |
Refractive Index | 1.4593 (estimate) |
MDL | MFCD00210248 |
Physical and Chemical Properties | Colorless liquid, soluble in methanol, ethanol, DMSO and other organic solvents, from Acorus tatarinowii Schott, Rosaceae plants loquat leaves. |
UN IDs | 3172 |
HS Code | 29329990 |
Hazard Class | 6.1(a) |
Packing Group | II |
Reference Show more | 1. Fang Yunge, Wang Pengfei, Zhu Houda, etc. Study on quality standard of venenum bufonis and decoction pieces (venenum bufonis powder) [J]. Chinese Journal of Traditional Chinese Medicine, 2020, 29 (8). 2. Zhang Mei Li Yu, Sangye Xiaoxue. Study on plasma Medicinal Chemistry of Liushen pills [J]. Green Science and Technology 2017 000(012):237-240. 3. Cao Yueting, Cui, cocoa, Wu, Jiheng, et al. Study on the correlation of the components of the venom of Chinese big toad [J]. Chinese Journal of Traditional Chinese Medicine 2019(9). 4. Wu juanping, Xue Tao, Guo Lu, Zhang Yan. HPLC fingerprint and chemical pattern recognition of Huachansu capsules [J]. Journal of Pharmaceutical Analysis, 2020,40(11):1977-1985. 5. Zhang Mei-Tuo et al. [IF = 2.193]. "Strategic Combination of Isocratic and Gradient Elution for Simultaneous Separation of Polar compositions in Traditional Chinese Medicines by HPLC." J Anal Methods Chem. 2018;2018:7569283 6. [IF = 4.411] Yueting Cao et al."Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins."Molecules. 2019 Jan;24(19):3595 7. [IF=4.379] Cao Yueting et al."The impact of multiple climatic and geographic factors on the chemical defences of Asian toads (Bufo gargarizans Cantor)."Sci Rep-Uk. 2019 Nov;9(1):1-11 8. [IF=1.902] Ke-ke Cui et al."Quantitative analysis of multicomponents by a single marker and quality evaluation of Venenum Bufonis from different geographical origins."Biomed Chromatogr. 2019 Sep;33(9):e4555 |