458532-90-6 - Names and Identifiers
Name | 3-Chloropyridine-4-boronic acid pinacol ester
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Synonyms | 3-CHLOROPYRIDINE-4-BORONIC ACID PINACOL ESTER 3-Chloro-4-pyridineboronic acid pinacol ester 3-Chloropyridine-4-boronic acid pinacol ester 3-Chloropyridin-4-ylboronic acid pinacol ester 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 3-CHLORO-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)PYRIDINE 3-Chloro-4-(4,4,5,5,-thtraMethyl-[1,3,2]dioxaborolan-2-yl)pyridine Pyridine, 3-chloro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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CAS | 458532-90-6
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EINECS | 604-604-1 |
InChI | InChI=1/C11H15BClNO2/c1-10(2)11(3,4)16-12(15-10)8-5-6-14-7-9(8)13/h5-7H,1-4H3 |
458532-90-6 - Physico-chemical Properties
Molecular Formula | C11H15BClNO2
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Molar Mass | 239.51 |
Density | 1.14g/cm3 |
Melting Point | 103-108°C |
Boling Point | 324.4°C at 760 mmHg |
Flash Point | 150°C |
Vapor Presure | 0.000466mmHg at 25°C |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.505 |
MDL | MFCD06798249 |
458532-90-6 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
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Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
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WGK Germany | 2 |
458532-90-6 - Introduction
3-Chloropyridine-4-boronic acid pinacol ester is an important organic compound whose chemical formula is C12H16BClNO2.
Nature:
3-Chloropyridine-4-boronic acid pinacol ester is colorless crystal with high stability. It is solid at room temperature and soluble in organic solvents such as methanol and acetonitrile. It is insoluble in water.
Use:
3-Chloropyridine-4-boronic acid pinacol ester is an important reagent in organic synthesis. It is commonly used in metal catalyzed reactions, especially C- C bond coupling reactions, such as Suzuki coupling reactions. In addition, it is also widely used in pharmaceutical synthesis, pesticide synthesis and materials science.
Preparation Method:
3-Chloropyridine-4-boronic acid pinacol ester is prepared by a variety of methods, but it is usually completed by chemical synthesis. A common method is to react 3-chloropyridine with a boronic acid pinacol ester, under appropriate conditions.
Safety Information:
Regarding the toxicity and safety of 3-Chloropyridine-4-boronic acid pinacol ester, it is necessary to operate in accordance with the chemical handling and use specifications. It is a kind of organic matter, potential toxicity and danger need attention. When in use, should wear protective gloves, glasses and masks, avoid direct contact with the skin and inhalation of its vapors. In addition, it should be handled in a well-ventilated area, and the compound should be stored and handled properly to avoid contact with combustibles, oxidants, etc. If an accidental leak or inhalation occurs, seek medical help immediately.
Last Update:2024-04-09 21:54:55