Name | Vandetanib |
Synonyms | ZD-6474 AZD-6474 HSDB 8198 Vandetanib VANDETANIB VANDETANIB FUMARATE Vandetanib, Zactima, ZD6474 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazolin-4-amine N-(4-bromo-2-fluoro-phenyl)-6-methoxy-7-[(1-methyl-4-piperidyl)methoxy]quinazolin-4-amine (4-BROMO-2-FLUORO-PHENYL)-[6-METHOXY-7-(1-METHYL-PIPERIDIN-4-YLMETHOXY)-QUINAZOLIN-4-YL]-AMINE |
CAS | 443913-73-3 338992-00-0 |
InChI | InChI=1/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27) |
Molecular Formula | C22H24BrFN4O2 |
Density | 1.406g/cm3 |
Boling Point | 538.22°C at 760 mmHg |
Flash Point | 279.306°C |
Solubility | Soluble in methanol, DMSO (4 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol |
Vapor Presure | 0mmHg at 25°C |
Storage Condition | -20℃ |
Refractive Index | 1.629 |
Use | An antagonist of VEGFR (Flk and Flk) and EGFR families. |