42491-79-2 - Names and Identifiers
42491-79-2 - Physico-chemical Properties
42491-79-2 - Introduction
Propanoic acid, 2-hydroxy-3-[[(phenylmethoxy)carbonyl]amino]-, (2S)-is an organic compound with the chemical formula C≡alcoH≡N O₂. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Propanoic acid, 2-hydroxy-3-[[(phenylmethoxy)carbonyl]amino]-, (2S)-is a white crystalline solid.
-Melting point: about 130-132 ℃.
-Solubility: Insoluble in water, but soluble in some organic solvents such as chloroform, dimethyl sulfoxide and dichloromethane.
Use:
- Propanoic acid, 2-hydroxy-3-[[(phenylmethoxy)carbonyl]amino]-, (2S)-is an important organic synthesis intermediate, often used in drug synthesis.
-It can be used in the synthesis of certain drugs, such as tyrosine hydroxylase inhibitors and amino acid derivatives.
Preparation Method:
The preparation method of
- Propanoic acid, 2-hydroxy-3-[[(phenylmethoxy)carbonyl]amino]-, (2S)-is relatively complicated and requires multi-step reactions. The usual synthetic route includes the following steps:
1. First, (S)-2-hydroxy-3-aminopropionic acid in dimethyl sulfoxide is reacted to produce (S)-2-chloro-3-aminopropionic acid.
2. The resulting chloride is then reacted with benzyl alcohol to produce Cbz-(S)-3-amino-2-chloropropionic acid.
3. Finally, by reacting with dimethyl carbonate, Propanoic acid, 2-hydroxy-3-[[(phenylmethoxy)carbonyl]amino]-, (2S)-are generated-.
Safety Information:
-Relevant safety information Propanoic acid, 2-hydroxy-3-[[(phenylmethoxy)carbonyl]amino]-, (2S)-has not been fully studied.
-During handling and storage, the safe handling of chemicals should be observed, and contact with skin, eyes and inhalation should be avoided.
-In case of accidental contact or inhalation, rinse immediately with water and seek medical advice.
Please note that the information provided here is for reference only. In actual use, please refer to the relevant literature, material safety data sheets and specific information provided by the manufacturer.
Last Update:2024-04-09 21:01:54