40032-73-3 - Names and Identifiers
40032-73-3 - Physico-chemical Properties
Molecular Formula | C4H2BrClS
|
Molar Mass | 197.48 |
Density | 1.808g/mLat 25°C(lit.) |
Boling Point | 70°C9mm Hg(lit.) |
Flash Point | 215°F |
Water Solubility | < 0.2 g/l (20 ºC) |
Vapor Presure | 0.536mmHg at 25°C |
Appearance | clear liquid |
Specific Gravity | 1.827 |
Color | Colorless to Yellow to Orange |
BRN | 1205539 |
Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
Refractive Index | n20/D 1.6(lit.) |
MDL | MFCD00043883 |
40032-73-3 - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin.
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S37/39 - Wear suitable gloves and eye/face protection
|
UN IDs | 2810 |
WGK Germany | 3 |
HS Code | 29349990 |
Hazard Class | IRRITANT |
Packing Group | II |
40032-73-3 - Introduction
3-Bromo-2-chroothiophene (3-Bromo-2-chroothiophene) is an organic compound with the chemical formula C4H2BrClS. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-Bromo-2-chroothiophene is a colorless to light yellow liquid with a special sulfur flavor.
-Solubility: It is soluble in organic solvents, such as chloroform, ethanol and carbon disulfide.
-Melting point: approximately -14 to -11°C.
-Boiling point: about 165 to 170 ℃.
-Density: about 1.922g/cm³.
Use:
-Chemical reagent: 3-Bromo-2-chroothiophene is a commonly used intermediate and reagent, often used in organic synthesis reactions.
-Drug research: It can be used to synthesize drugs and drug intermediates, such as anti-tumor agents, antibacterial agents, etc.
Preparation Method:
3-Bromo-2-chorothiophene can be synthesized:
1. In the reaction of 2-chlorothiophene, cuprous bromide (CuBr) is added to react with cuprous bromide (CuCl) to obtain 2-bromo-3-chlorothiophene.
2. Next, sodium hydride (NaH) and copper sulfide (CuS) were added to 2-bromo-3-chlorothiophene to react with the sulfide to obtain 3-Bromo-2-chlorothiophene.
Safety Information:
3-Bromo-2-chroothiophene is generally considered to be relatively safe under normal operating conditions. However, in the process of handling and use, the following safety measures should be paid attention:
-Personal safety: Avoid direct contact with the substance as it may have an irritating effect on the skin, eyes and respiratory system. Wear appropriate protective gloves, goggles and protective mask during operation.
-Fire hazard: 3-Bromo-2-chroothiophene is a flammable liquid and should be kept away from open flames and high temperature sources. Pay attention to fire prevention measures during use and storage.
-Toxicity: There are not many toxicity data for this compound, but the safe practice of general chemicals should still be followed.
When using 3-Bromo-2-chlorothiophene, follow appropriate laboratory procedures and strictly follow safety guidelines. In case of accident or discomfort, seek medical help.
Last Update:2024-04-09 20:45:29