4-hydrazinylbenzonitrile - Names and Identifiers
4-hydrazinylbenzonitrile - Physico-chemical Properties
Molecular Formula | C7H7N3
|
Molar Mass | 133.15 |
Density | 1.19 |
Melting Point | 91-93 °C |
Boling Point | 325.9±25.0 °C(Predicted) |
pKa | 4.11±0.20(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
4-hydrazinylbenzonitrile - Introduction
Cyanophenylhydrazine is an organic compound with the chemical formula C6H4(NH-NH2)(CN). The following is a description of the nature, use, preparation and safety information of 4-hydrazinylbenzonitril:
Nature:
1. Appearance: cyanophenylhydrazine is colorless crystal or white powder.
2. Melting Point: about 240-245 ° C.
3. Solubility: Cyanophenylhydrazine is almost insoluble in water, but can be dissolved in organic solvents such as methanol, ethanol and acetonitrile.
Use:
1. Cyanophenylhydrazine can be used as a reducing agent in organic synthesis.
2. It can react with aldehydes, ketones and other compounds to generate the corresponding phenylhydrazine compounds, and has selectivity.
3. Cyanophenylhydrazine can also be used to synthesize other organic compounds, such as adenine analogs and heterocyclic compounds.
Method:
1. Cyanophenylhydrazine can usually be obtained by reacting O-nitrophenylhydrazine with Cyanogen chloride. First, O-nitrophenylhydrazine reacts with sodium nitrosate to form a nitro compound, then through a reduction reaction to form an amino compound, and finally reacts with Cyanogen chloride to form cyanophenylhydrazine.
2. The preparation process needs to pay attention to controlling the reaction temperature and the purity of cyanophenylhydrazine to ensure safety and product quality.
Safety Information:
1. Cyanophenylhydrazine is toxic and may be harmful to human health by inhalation or exposure. Wear appropriate personal protective equipment such as gloves, goggles and protective clothing during use and operation.
2. In the process of preparation and treatment, care should be taken to avoid contact with oxidants, strong acids, strong bases and combustibles to prevent dangerous chemical reactions.
3. During storage, the cyanophenylhydrazine should be stored in a dry, cool, well-ventilated place, away from ignition and flammable materials.
4. When disposing of waste, it should be disposed according to local environmental regulations to avoid environmental pollution.
Please note that the preparation and use of cyanophenylhydrazine involves some chemical operations and safety risks, and it is recommended to proceed under the guidance of an experienced chemical laboratory or professional.
Last Update:2024-04-10 22:29:15