4-Pyrimidinamine, 5-methoxy- (9CI)
4-Amino-5-methoxypyrimidine
CAS: 695-86-3
Molecular Formula: C5H7N3O
4-Pyrimidinamine, 5-methoxy- (9CI) - Names and Identifiers
| Name | 4-Amino-5-methoxypyrimidine |
| Synonyms | 5-methoxypyrimidin-4-amine 4-amino-5-methoxypyrimdine 5-Methoxy-4-pyrimidinamine 5-MethoxypyriMidin-4-aMine 4-Amino-5-methoxypyrimidine 4-Pyrimidinamine, 5-methoxy- 4-Pyrimidinamine, 5-Methoxy- 4-Pyrimidinamine, 5-methoxy- (9CI) |
| CAS | 695-86-3 |
| InChI | InChI=1/C5H7N3O/c1-9-4-2-7-3-8-5(4)6/h2-3H,1H3,(H2,6,7,8) |
4-Pyrimidinamine, 5-methoxy- (9CI) - Physico-chemical Properties
| Molecular Formula | C5H7N3O |
| Molar Mass | 125.13 |
| Density | 1.224±0.06 g/cm3(Predicted) |
| Melting Point | 118.5-119.0 °C |
| Boling Point | 264.3±20.0 °C(Predicted) |
| Flash Point | 113.6°C |
| Vapor Presure | 0.00981mmHg at 25°C |
| pKa | 5.04±0.10(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.566 |
4-Pyrimidinamine, 5-methoxy- (9CI) - Introduction
4-Amino-5-methoxypyrimidine(4-Amino-5-methoxypyrimidine) is an organic compound with the molecular formula C5H7N3O and a molecular weight of 125.13g/mole. The following is a description of its nature, use, preparation and safety information:
Nature:
1. Appearance: 4-Amino-5-methoxypyrimidine exists in the form of white crystals.
2. Solubility: It is soluble in water, alcohol and ether.
Use:
1. Drug synthesis: 4-Amino-5-methoxypyrimidine is an important intermediate for the synthesis of various drugs, such as anti-tumor drugs.
2. Pesticide synthesis: It is also used to synthesize certain pesticides, such as herbicides and insecticides.
Preparation Method:
4-Amino-5-methoxypyrimidine has many preparation methods, the following is one of them:
Step 1: Add pyrimidine to methyl chloride, and add methyl alcohol and hydrochloric acid catalyst.
Step 2: Aqueous ammonia was slowly added dropwise to the reaction solution.
Step 3: Stir at room temperature to allow the reaction to continue.
Step 4: The reaction solution was separated by filtration and then washed with hydrochloric acid.
Step 5: The product was purified by vacuum distillation or crystallization.
Safety Information:
1. 4-Amino-5-methoxypyrimidine needs to be operated in a well-ventilated place to avoid inhaling its dust or vapor.
2. It is irritating to eyes and skin, and contact with skin and eyes should be avoided.
3. use should wear protective gloves and goggles and other personal protective equipment.
4. Keep sealed during storage and handling to avoid contact with oxidants and strong acids.
Nature:
1. Appearance: 4-Amino-5-methoxypyrimidine exists in the form of white crystals.
2. Solubility: It is soluble in water, alcohol and ether.
Use:
1. Drug synthesis: 4-Amino-5-methoxypyrimidine is an important intermediate for the synthesis of various drugs, such as anti-tumor drugs.
2. Pesticide synthesis: It is also used to synthesize certain pesticides, such as herbicides and insecticides.
Preparation Method:
4-Amino-5-methoxypyrimidine has many preparation methods, the following is one of them:
Step 1: Add pyrimidine to methyl chloride, and add methyl alcohol and hydrochloric acid catalyst.
Step 2: Aqueous ammonia was slowly added dropwise to the reaction solution.
Step 3: Stir at room temperature to allow the reaction to continue.
Step 4: The reaction solution was separated by filtration and then washed with hydrochloric acid.
Step 5: The product was purified by vacuum distillation or crystallization.
Safety Information:
1. 4-Amino-5-methoxypyrimidine needs to be operated in a well-ventilated place to avoid inhaling its dust or vapor.
2. It is irritating to eyes and skin, and contact with skin and eyes should be avoided.
3. use should wear protective gloves and goggles and other personal protective equipment.
4. Keep sealed during storage and handling to avoid contact with oxidants and strong acids.
Last Update：2024-04-09 02:00:47
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Spot supply
Product Name: 5-Methoxypyrimidin-4-amine Visit Supplier Webpage Request for quotationCAS: 695-86-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 5-Methoxypyrimidin-4-amine Visit Supplier Webpage Request for quotationCAS: 695-86-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
4-Pyrimidinamine, 5-methoxy- (9CI)
Acid orange 156 (C.I. 26501)
4-[(2-氨基乙基)(5-氯-2-苯并恶唑基)氨基]-2-丁烷酮(二甲磺酸盐)
3-碘-4-甲氧基苯甲酸乙酯
1-二甲氨基-3-[2-[2-(3-甲氧基苯基)乙基]苯氧基]-2-丙醇盐酸盐
Radix Cyathulae extract
Co-Formula CFS-125
2,6-二氯嘌呤核苷(2,6-DICHLOROPURINE RIBOSIDE)
AMILORIDE-15N3 HYDROCHLORIDE
托匹司他杂质B
Acid orange 156 (C.I. 26501)
4-[(2-氨基乙基)(5-氯-2-苯并恶唑基)氨基]-2-丁烷酮(二甲磺酸盐)
3-碘-4-甲氧基苯甲酸乙酯
1-二甲氨基-3-[2-[2-(3-甲氧基苯基)乙基]苯氧基]-2-丙醇盐酸盐
Radix Cyathulae extract
Co-Formula CFS-125
2,6-二氯嘌呤核苷(2,6-DICHLOROPURINE RIBOSIDE)
AMILORIDE-15N3 HYDROCHLORIDE
托匹司他杂质B