4-Nitro-2-(trifluoromethoxy)aniline - Names and Identifiers
4-Nitro-2-(trifluoromethoxy)aniline - Physico-chemical Properties
Molecular Formula | C7H5F3N2O3
|
Molar Mass | 222.12 |
Density | 1.543±0.06 g/cm3(Predicted) |
Boling Point | 306.2±37.0 °C(Predicted) |
pKa | -1.27±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
4-Nitro-2-(trifluoromethoxy)aniline - Introduction
2-Trifluoromethoxy-4-nitroaniline is an organic compound with the chemical formula C7H5F3N2O2. The following is a description of its nature, use, preparation and safety information:
Nature:
2-Trifluoromethoxy-4-nitroaniline is a white crystalline solid with a melting point of about 68-72 degrees Celsius. It is soluble in organic solvents such as methanol, ethanol and dichloromethane at normal temperature.
Use:
2-Trifluoromethoxy-4-nitroaniline can be used as an intermediate compound in organic synthesis. It has a wide range of applications in the field of pesticides, pharmaceuticals and dyes. In addition, it acts as an oxidant and dopamine receptor antagonist.
Method:
The preparation method of 2-trifluoromethoxy-4-nitroaniline is usually obtained by nitration reaction. First, p-aminophenol is reacted with trifluoromethyl alcohol to produce 2-trifluoromethoxyaniline. Then, 2-trifluoromethoxyaniline is reacted with nitric acid, and nitration occurs under appropriate conditions to obtain 2-trifluoromethoxy-4-nitroaniline.
Safety Information:
2-Trifluoromethoxy-4-nitroaniline is toxic to human body, irritating and corrosive. During use, care should be taken to avoid contact with skin and eyes, and require operation in a well-ventilated place. In addition, appropriate protective gloves, goggles and protective clothing must be worn when handling the compound. During storage and transportation, it should be kept away from fire and oxidant, stored in a cool and dry place, and avoid mixing with other organic substances.
Last Update:2024-04-09 21:01:54