Name | 4-Fluoroaniline |
Synonyms | 4-Fluoranilin 4-fluoro-anilin 4-Fluoroaniline 4-Fluoronaniline p-Fluoroaniline Fluoroaniline, 4- Aniline, p-fluoro- Aniline, 4-fluoro- Parafluoro Aniline butyl fluoroacetate 4-fluoro-benzenamin 4-fluoranilin(czech) 4-Fluoro-phenylamine 1,4-fluorobenzenamine Fluoroanilinepaleredliq Benzenamine, 4-fluoro- |
CAS | 371-40-4 |
EINECS | 206-735-5 |
InChI | InChI:1S/C6H6FN/c7-5-1-3-6(8)4-2-5/h1-4H,8H2 |
Molecular Formula | C6H6FN |
Molar Mass | 111.12 |
Density | 1.173 g/mL at 25 °C (lit.) |
Melting Point | -1.9 °C |
Boling Point | 187 °C/767 mmHg (lit.) |
Flash Point | 165°F |
Water Solubility | 33 g/L (20 ºC) |
Solubility | 33g/l |
Vapor Presure | 4.04mmHg at 25°C |
Appearance | Oily Liquid |
Specific Gravity | 1.173 |
Color | Clear pale yellow to red-brown |
Merck | 14,4169 |
BRN | 742030 |
pKa | 4.65(at 25℃) |
Storage Condition | 2-8°C |
Stability | Stable. Incompatible with acids, oxidizing agents. |
Refractive Index | n20/D 1.539(lit.) |
Physical and Chemical Properties | Density 1.1586 melting point -1.9°C boiling point 187°C refractive index 1.5385-1.5405 flash point 81°C water-soluble 33g/L (20°C) |
Use | Used as intermediates in the synthesis of pharmaceuticals, dyes and pesticides |
Risk Codes | R22 - Harmful if swallowed R34 - Causes burns R36/38 - Irritating to eyes and skin. R33 - Danger of cumulative effects R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S37/39 - Wear suitable gloves and eye/face protection S28 - After contact with skin, wash immediately with plenty of soap-suds. |
UN IDs | UN 2941 6.1/PG 3 |
WGK Germany | 1 |
RTECS | BY1575000 |
TSCA | T |
HS Code | 29214210 |
Hazard Note | Toxic/Irritant |
Hazard Class | 6.1 |
Packing Group | III |
liquid. Melting Point -0.82 ℃, boiling point 184~186 ℃, relative density 1.1725, refractive index 1.51954.
There are a variety of synthetic routes, which can be divided into one-step method and two-step method.
for the synthesis of new fluorine-containing drugs, pesticides and dyes.
This product can burn when exposed to open fire. The flash point is 73 ° C, and the toxic gas is decomposed by high heat, which is irritating to the human body. Rat oral LD50: 615mg/kg; Mouse oral LD50:417mg/kg. Packaging using iron plastic barrel, 200/barrel, stored in a cool and dry place, no contact with fire, no sun exposure, pay attention to light light unloading, to prevent container damage.