Name | 4-Butylresorcinol |
Synonyms | 4-Butylresorcinol 4-N-BUTYLRESORCINOL 4-Butylbenzene-1,3-diol 4-phenylbutane-1,3-diol 1,3-Benzenediol,4-butyl- 2,4-Dihydroxy-n-bytyl benzen 2,4-DIHYDROXY-N-BUTYL BENZEN 2,4-DIHYDROXY-N-BUTYL BENZENE 4-06-00-06003 (Beilstein Handbook Reference 4-06-00-06003 (Beilstein Handbook Reference) |
CAS | 18979-61-8 |
InChI | InChI=1/C10H14O2/c1-2-3-4-8-5-6-9(11)7-10(8)12/h5-7,11-12H,2-4H2,1H3 |
InChIKey | CSHZYWUPJWVTMQ-UHFFFAOYSA-N |
Molecular Formula | C10H14O2 |
Molar Mass | 166.22 |
Density | 1.092±0.06 g/cm3(Predicted) |
Melting Point | 50.0 to 55.0 °C |
Boling Point | 166°C/7mmHg(lit.) |
Flash Point | 144.5°C |
Vapor Presure | 0.041Pa at 25℃ |
Appearance | Yellow or white powder |
Color | white to pale yellow powder |
pKa | 9.95±0.18(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.555 |
Use | This product is for scientific research only and shall not be used for other purposes. |
In vitro study | It shows that 4-Butylresorcinol (4-n-butylresorcinol) significantly inhibits melanin synthesis in a concentration-dependent manner. In addition, it is also found to inhibit the activity of tyrosinase, the rate-limiting melanogenic enzyme. 4-Butylresorcinol does not induce ERK, Akt activation, or MITF degradation, and has no effect on cAMP response element binding protein (CREB) phosphorylation, which stimulates MITF expression. 4-Butylresorcinol strongly reduces tyrosinase activity in a cell-free system. Moreover, 4-Butylresorcinol shows an additive effect in combination with hinokitiol, which reduces MITF expression. |
RTECS | VH0420000 |