4-(Bromomethyl)-1-chloro-2-fluorobenzene, alpha-Bromo-4-chloro-3-fluorotoluene
3-Fluoro-4-chlorobenzyl bromide
CAS: 206362-80-3
Molecular Formula: C7H5BrClF
4-(Bromomethyl)-1-chloro-2-fluorobenzene, alpha-Bromo-4-chloro-3-fluorotoluene - Names and Identifiers
4-(Bromomethyl)-1-chloro-2-fluorobenzene, alpha-Bromo-4-chloro-3-fluorotoluene - Physico-chemical Properties
| Molecular Formula | C7H5BrClF |
| Molar Mass | 223.47 |
| Density | 1.654±0.06 g/cm3(Predicted) |
| Melting Point | 30-33℃ |
| Boling Point | 227.1±25.0 °C(Predicted) |
| Flash Point | 91.1°C |
| Solubility | soluble in Methanol |
| Vapor Presure | 0.119mmHg at 25°C |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Sensitive | Lachrymatory |
| Refractive Index | 1.561 |
4-(Bromomethyl)-1-chloro-2-fluorobenzene, alpha-Bromo-4-chloro-3-fluorotoluene - Risk and Safety
| Hazard Symbols | C - Corrosive |
| Risk Codes | 34 - Causes burns |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 3261 |
| HS Code | 29039990 |
| Hazard Note | Corrosive/Lachrymatory |
| Hazard Class | CORROSIVE |
| Packing Group | Ⅱ |
4-(Bromomethyl)-1-chloro-2-fluorobenzene, alpha-Bromo-4-chloro-3-fluorotoluene - Introduction
3-fluoro-4-chorobenzyl bromide, chemical formula C7H4ClFBr, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid or crystal.
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide.
-Melting point: About 50-60 degrees Celsius.
-Boiling point: About 220-230 degrees Celsius.
Use:
-3-fluoro-4-chloride bromide is an important raw material in organic synthesis. It can be used as a ligand of metal catalyst and participate in organic synthesis reaction.
-It can also be used for research and development in the pharmaceutical field, for the synthesis of drugs or pharmaceutical intermediates.
Method:
-A common preparation method is to react 3-fluorobenzyl alcohol with hydrogen oxide to prepare 3-fluorobenzaldehyde, the 3-fluorobenzaldehyde is then reacted with dibromomethane to give 3-fluoro-4-bromobenzaldehyde. Finally, 3-fluoro-4-bromobenzaldehyde was converted to 3-Fluoro-4-chlorobenzyl bromide by chlorination.
Safety Information:
- 3-Fluoro-4-chlorobenzyl bromide should be operated in a well-ventilated place to avoid inhalation or contact.
-Wear protective gloves, goggles and protective clothing when using.
-Avoid contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Avoid contact with oxidants and high-temperature substances during use and storage to avoid chemical reactions and fires.
-Please store, transport and handle in accordance with relevant laws and regulations.
Nature:
-Appearance: colorless liquid or crystal.
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide.
-Melting point: About 50-60 degrees Celsius.
-Boiling point: About 220-230 degrees Celsius.
Use:
-3-fluoro-4-chloride bromide is an important raw material in organic synthesis. It can be used as a ligand of metal catalyst and participate in organic synthesis reaction.
-It can also be used for research and development in the pharmaceutical field, for the synthesis of drugs or pharmaceutical intermediates.
Method:
-A common preparation method is to react 3-fluorobenzyl alcohol with hydrogen oxide to prepare 3-fluorobenzaldehyde, the 3-fluorobenzaldehyde is then reacted with dibromomethane to give 3-fluoro-4-bromobenzaldehyde. Finally, 3-fluoro-4-bromobenzaldehyde was converted to 3-Fluoro-4-chlorobenzyl bromide by chlorination.
Safety Information:
- 3-Fluoro-4-chlorobenzyl bromide should be operated in a well-ventilated place to avoid inhalation or contact.
-Wear protective gloves, goggles and protective clothing when using.
-Avoid contact with skin and eyes. In case of accidental contact, rinse immediately with plenty of water and seek medical help.
-Avoid contact with oxidants and high-temperature substances during use and storage to avoid chemical reactions and fires.
-Please store, transport and handle in accordance with relevant laws and regulations.
Last Update：2024-04-09 21:00:56
Supplier List
Spot supply
Product Name: 4-Chloro-3-fluorobenzyl broMide Visit Supplier Webpage Request for quotationCAS: 206362-80-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 4-Chloro-3-fluorobenzyl bromide Visit Supplier Webpage Request for quotationCAS: 206362-80-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-Chloro-3-fluorobenzyl bromide Visit Supplier Webpage Request for quotationCAS: 206362-80-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: 4-Chloro-3-fluorobenzyl broMide Visit Supplier Webpage Request for quotationCAS: 206362-80-3
Tel: +86 0571-86722205
Email: sales@chinaskyrun.com
Mobile: +8618958170122
QQ: 2531159185
Wechat: chinaskyrun
Spot supply
Product Name: 4-Chloro-3-fluorobenzyl bromide Visit Supplier Webpage Request for quotationCAS: 206362-80-3
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: 4-Chloro-3-fluorobenzyl bromide Visit Supplier Webpage Request for quotationCAS: 206362-80-3
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
4-(Bromomethyl)-1-chloro-2-fluorobenzene, alpha-Bromo-4-chloro-3-fluorotoluene
BENZONITRILE-D5
Isoxazole, 3-(3-bromophenyl)-5-chloro-
29582-19-2
3,3-Dimethylpiperidin-4-amine
2-(1,3-Dimethyl-2,4,6-trioxo-2,3,4,5,6,7-hexahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)acetic acid
1,2-Pyrrolidinedicarboxylic acid, 3-phenyl-, 1-(9H-fluoren-9-ylmethyl) ester, (2R,3R)-
THIONIN ACETATE
1-[(2,5-dimethoxyphenyl)sulfonyl]-N-(1-phenylethyl)-4-piperidinecarboxamide
847503-16-6
BENZONITRILE-D5
Isoxazole, 3-(3-bromophenyl)-5-chloro-
29582-19-2
3,3-Dimethylpiperidin-4-amine
2-(1,3-Dimethyl-2,4,6-trioxo-2,3,4,5,6,7-hexahydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)acetic acid
1,2-Pyrrolidinedicarboxylic acid, 3-phenyl-, 1-(9H-fluoren-9-ylmethyl) ester, (2R,3R)-
THIONIN ACETATE
1-[(2,5-dimethoxyphenyl)sulfonyl]-N-(1-phenylethyl)-4-piperidinecarboxamide
847503-16-6