4-(2,4-Difluorophenyl)piperidine - Names and Identifiers
4-(2,4-Difluorophenyl)piperidine - Physico-chemical Properties
Molecular Formula | C11H13F2N
|
Molar Mass | 197.22 |
Density | 1.126±0.06 g/cm3(Predicted) |
Boling Point | 235.8±40.0 °C(Predicted) |
Flash Point | 96.437°C |
Vapor Presure | 0.049mmHg at 25°C |
pKa | 10.03±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.492 |
4-(2,4-Difluorophenyl)piperidine - Introduction
4-(2,4-difluorophenyl) piperidine is an organic compound with the chemical structure C11H14F2N. It is a compound containing a piperidine ring in which a difluorophenyl group is attached to the 4 carbon atom of the piperidine ring.
Regarding its properties, 4-(2,4-difluorophenyl) piperidine is a colorless or light yellow liquid with a special nitrogen heterocyclic odor at room temperature. It has low density, strong solubility, soluble in many organic solvents such as ethanol, toluene and dichloromethane. The compound is stable in air, but its solution may decompose under light.
4-(2,4-difluorophenyl) piperidine is commonly used as an intermediate in organic synthesis and pharmaceutical synthesis. It can be used to synthesize a variety of organic compounds, such as drugs and ligands in the field of medicine. This compound also has some biological activity in pharmaceutical research.
The method for preparing 4-(2,4-difluorophenyl) piperidine includes the reaction of piperidine and 2,4-difluorophenyl bromide. Usually, the piperidine is dissolved in a suitable solvent, and then an excess of 2,4-difluorophenyl bromide is added, and the reaction is carried out under the irradiation of a tungsten lamp or ultraviolet light. After completion of the reaction, the product can be purified by process steps such as extraction and distillation.
For safety information, 4-(2,4-difluorophenyl) piperidine is not currently listed in the Special Dangerous Goods category. However, as an organic compound, it may have irritating effects on the skin, eyes and respiratory system. Therefore, appropriate protective measures should be taken during use and operation, such as wearing protective gloves, goggles and face shields. In addition, work should be done in a well-ventilated area to avoid exposure to large amounts of compounds. If accidental exposure or ingestion occurs, medical help should be sought immediately.
Last Update:2024-04-09 21:54:55