4-羟基-3-羟甲基-Α-溴苯乙酮二乙酸酯

4-羟基-3-羟甲基-Α-溴苯乙酮二乙酸酯 - Names and Identifiers

Name	1-(4-Acetyloxy)-3-((acetyloxy)methyl)phenyl)-2-bromoethanone
Synonyms	2-AcetoxyMethyl-4-broMophenyl Acetate 2-acetoxy-5-(2-bromoacetyl)benzyl acetate 4-Acetoxy-3-acetoxyMethyl-α-broMoacetophenone 4-Acetoxy-3-acetoxymethyl-a-bromoacetophenone 4-Hydroxy-3-hydroxymethyl-bromoace-tophenone diacetate 4-Hydroxy-3-Hydroxynethyl-A-Bromoacetophenone Diacetate 2-BroMo-4'-hydroxy-3'-(hydroxyMethyl)acetophenone Diacetate 1-(4-Acetyloxy)-3-((acetyloxy)methyl)phenyl)-2-bromoethanone
CAS	24085-07-2

4-羟基-3-羟甲基-Α-溴苯乙酮二乙酸酯 - Physico-chemical Properties

Molecular Formula	C13H13BrO5
Molar Mass	329.14
Density	1.465±0.06 g/cm3(Predicted)
Boling Point	428.7±45.0 °C(Predicted)
Solubility	Chloroform, Dichloromethane
Appearance	Oil
Color	Brown
Storage Condition	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
Use	Use is an intermediate of salbutamol.

4-羟基-3-羟甲基-Α-溴苯乙酮二乙酸酯 - Production method

The p-hydroxyacetophenone is chloromethylated with formaldehyde and concentrated hydrochloric acid to generate 3-chloromethyl-4-hydroxyacetophenone, and then esterified with acetic anhydride to obtain 3-hydroxymethyl-4-hydroxyacetophenone diacetate, the latter is brominated with bromine to obtain the product.

Last Update：2024-04-10 22:29:15

4-羟基-3-羟甲基-Α-溴苯乙酮二乙酸酯 - Reference Information

use	salbutamol intermediate.
production method	p-hydroxyacetophenone is chloromethylated with formaldehyde and concentrated hydrochloric acid to generate 3-chloromethyl-4-hydroxyacetophenone, and then esterified with acetic anhydride to obtain 3-hydroxymethyl-4-hydroxyacetophenone diacetate, which is brominated with bromine to obtain the product.

Last Update：2024-04-09 21:04:16