Name | 4'-Demethylepipodophyllotoxin |
Synonyms | Demethylpodophyllotoxin, 4'- 4'-Demethylepipodophyllotoxin 4'-Demethylepipodo phyllotoxin 4'-O-deMethylepipodophyllotoxin 4-DeMethyl Epipodophyllotoxin(DMEP) 4-Domethylpodophyllotoxin, 4'-demethyl-epi-Podophyllotoxin (5R)-5β-(3,5-Dimethoxy-4-hydroxyphenyl)-7α-(hydroxymethyl)-8α-hydroxy-5,6,7,8-tetrahydronaphtho[2,3-d]-1,3-dioxole-6β-carboxylic acid 6,7-lactone |
CAS | 6559-91-7 |
EINECS | 613-823-0 |
InChI | InChI=1/C21H20O7/c1-24-16-5-11(6-17(25-2)20(16)22)18-13-7-15-14(27-9-28-15)4-10(13)3-12-8-26-21(23)19(12)18/h4-7,12,18-19,22H,3,8-9H2,1-2H3/t12-,18+,19-/m0/s1 |
Molecular Formula | C21H20O8 |
Molar Mass | 400.38 |
Density | 1.446±0.06 g/cm3(Predicted) |
Melting Point | 246-248°C |
Boling Point | 626.5±55.0 °C(Predicted) |
Specific Rotation(α) | -69.8 (CHCl3) |
Flash Point | 211.8°C |
Solubility | Soluble in chloroform, acetone, ethyl acetate and benzene, soluble in ethanol, ether, insoluble in water |
Vapor Presure | 1.46E-14mmHg at 25°C |
Appearance | Light yellow to yellow (Solid) |
Color | White to Off-White |
pKa | 9.94±0.40(Predicted) |
Storage Condition | Inert atmosphere,Store in freezer, under -20°C |
Refractive Index | 1.616 |
MDL | MFCD00189421 |
Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from the seven peach, eight point Lotus, Chinese podophyllotoxin. |
HS Code | 29349990 |
biological activity | 4 '-demethyllepipodophyllotoxin (4'-DMEP) is an intermediate compound that inhibits microtubule assembly. |
Use | 4 '-demethylepipodophyllotoxin has anti-inflammatory and anti-tumor effects. for content determination/identification/pharmacological experiments. Pharmacological Efficacy: podophyllotoxin and its derivatives are a class of lignans with significant physiological activity, the physiological activity of the main performance of anti-tumor activity and antiviral activity. |