Name | 3-Amino-1-propanesulfonic acid |
Synonyms | 3 APS HOMOTAURINE Homotaurine TRAMIPROSATE 3-AMINOPROPANESULFONIC ACID 3-Amino-1-propanesulfonic acid 3-AMINOPROPANE-1-SULFONIC ACID 3-AMINO-1-PROPANESULFONIC ACID 3-aminopropane-1-sulphonic acid aminopropanesulfonicacid,3-aminopropanesulfonicacid |
CAS | 3687-18-1 |
EINECS | 222-977-4 |
InChI | InChI=1/C3H9NO3S/c4-2-1-3-8(5,6)7/h1-4H2,(H,5,6,7) |
Molecular Formula | C3H9NO3S |
Molar Mass | 139.17 |
Density | 1.202 (estimate) |
Melting Point | 293°C (dec.)(lit.) |
Solubility | Water (Slightly) |
Appearance | Crystalline Powder |
Color | White to slightly blue |
pKa | 1.06±0.50(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.5130 (estimate) |
MDL | MFCD00008225 |
Use | As an intermediate of acamprosate, a therapeutic agent for alcoholism |
In vitro study | Tramiprosate (200 μg/mL, 40 μg/mL, 8 μg/mL and 1.6 μg/mL; 1 hours) significantly attenuates oxygen/glucose deprivation (OGD)- or NMDA-induced injury in NGF-differentiated PC12 cells and primary cortical neurons. Tramiprosate decreases the intensity of the association between nNOS and PSD95, and Tramiprosate also inhibits the translocation of nNOS from the cytosol to the membrane. |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 1 |
HS Code | 29049090 |