34218-84-3 - Names and Identifiers
Name | Uridine,5-iodo-2'-O-methyl- (8CI,9CI)
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Synonyms | 5-I-2'-OMe-U 2'-OMe-5-I-U 5-I-2'-OME-RU 2'-OMe-5-I-Uridine 5-Iodo-2'-OMe-2'-dU 5-IODO-2'-O-METHYLURIDINE 2'-O-methyl-5-Iodo-Uridine 2'-(O-METHYL)-5-IODOURIDINE Uridine, 5-iodo-2'-O-Methyl- Uridine,5-iodo-2'-O-methyl- (8CI,9CI)
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CAS | 34218-84-3
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EINECS | 2017-001-1 |
34218-84-3 - Physico-chemical Properties
Molecular Formula | C10H13IN2O6
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Molar Mass | 384.12 |
Density | 2.04±0.1 g/cm3(Predicted) |
pKa | 7.94±0.10(Predicted) |
34218-84-3 - Introduction
Uridine,5-iodo-2 '-O-methyl- (8CI,9CI) is a chemical compound with the formula C10H12IN2O6 and a molecular weight of 376.12g/mol. It is a derivative of uridine in which carbon atom 5 of uracil is replaced by an iodine atom and the-OH group at the 2 'position is replaced by a methoxy group (-OCH3).
Properties of Uridine,5-iodo-2 '-O-methyl- (8CI,9CI):
-Appearance: Colorless crystalline solid
-Melting point: 233-235°C
-Solubility: can be dissolved in water and methanol
Uridine,5-iodo-2 '-O-methyl- (8CI,9CI) Usage:
Uridine,5-iodo-2 '-O-methyl- (8CI,9CI) is a nucleoside compound, which plays an important role in drug development and biological science research. It can act as an inhibitor of synthetic transcriptase and translational enzymes, thereby inhibiting the process of nucleic acid synthesis. In addition, it can also be used as a labeling reagent for synthetic ribonucleic acid (RNA).
Method of preparing Uridine,5-iodo-2 '-O-methyl- (8CI,9CI):
The common preparation method is to react uridine with iodoethanol, and then deprotect the methoxy group with hydrofluoric acid (HF) to form Uridine,5-iodo-2 '-O-methyl- (8CI,9CI).
Safety information for Uridine,5-iodo-2 '-O-methyl- (8CI,9CI):
Because of its strong toxicity and irritation, it is necessary to pay attention to safety when using and handling. Wear appropriate protective equipment, such as lab gloves and glasses, when using or handling the compound. In addition, the operation should be carried out in a well-ventilated area, avoiding inhalation or contact with skin. In the event of accidental exposure or inhalation of this compound, seek medical attention immediately.
Last Update:2024-04-09 20:52:54