339286-31-6 - Names and Identifiers
Name | 7-Chloro-5-propylsulfanyl-1H-[1,2,3]triazolo[4,5-d]pyrimidine
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Synonyms | 7-Chloro-5-(propylthio)-3h-1,2,3-triazolo[4,5-d]pyrimidine 7-Chloro-5-(propylthio)-1H-[1,2,3]triazolo[4,5-d]pyrimidine 3H-1,2,3-Triazolo[4,5-d]pyrimidine, 7-chloro-5-(propylthio)- 7-Chloro-5-propylsulfanyl-1H-[1,2,3]triazolo[4,5-d]pyrimidine
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CAS | 339286-31-6
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339286-31-6 - Physico-chemical Properties
339286-31-6 - Introduction
-[1,2,3]triazolo[4,5-d]pyrimidine is an organic compound with the chemical formula C8H9ClN4S. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Melting point: 85-87°C
-Boiling point: 363°C
-Solubility: Soluble in ethanol, methanol and dichloromethane, insoluble in water
-Stability: Stable under dry conditions, but deliquescence
Use:
[1,2,3]triazolo[4,5-d]pyrimidine is a compound containing a triazole ring and a pyrimidine ring, so it has certain biological activity. It is widely used in the fields of medicine and pesticide, and has antifungal and antibacterial activities. In addition, it can also be used as a raw material or intermediate in organic synthesis.
Preparation Method:
The preparation method of [1,2,3]triazolo[4,5-d]pyrimidine can be achieved by the following steps:
1. pyrimidine -4, 6-dione reacts with tert-butyl ethyl carbamate (ethyl nicotinate) to generate ethyl N-(tert-butyl)-1,2, 3-triazole-4-carboxylate.
2. N-(tert-butyl)-1,2, 3-triazole-4-carboxylic acid ethyl ester is reacted with monochloroacetyl chloride to generate 7-chloro-5-propylsulfanyl-1, 2,3-triazolo [4,5-d] pyrimidine.
Safety Information:
Due to the lack of specific toxicity data, the safety evaluation of the pyrimidine-[1,2,3]triazolo[4,5-d] is very limited. As an organic compound, it can be potentially hazardous, including irritant and allergenic. Appropriate laboratory safety measures should be followed when using or handling the compound, such as wearing appropriate protective equipment (such as gloves and goggles) and ensuring good ventilation. When handling this compound, it is recommended to follow local safe practices.
Last Update:2024-04-09 20:52:54