Molecular Formula | C12H7Cl3O2 |
Molar Mass | 289.54 |
Density | 1.4214 (rough estimate) |
Melting Point | 56-60°C(lit.) |
Boling Point | 290°C(lit.) |
Flash Point | 313.7°C |
Water Solubility | Soluble in ethanol, methanol, diethyl ether and sodium hydroxide solution (1M). Slightly soluble in water. |
Solubility | H2O: soluble12g/L at 20°C |
Vapor Presure | 0.001Pa at 25℃ |
Appearance | Solid |
Color | colorless or white |
Merck | 14,9657 |
BRN | 2057142 |
pKa | 7.9(at 25℃) |
Storage Condition | 2-8°C |
Stability | Stable. Incompatible with strong oxidizing agents. |
Refractive Index | 1.4521 (estimate) |
MDL | MFCD00800992 |
Physical and Chemical Properties | Melting point 56-60°C |
Use | It is used for the production of high-grade daily chemical products, the preparation of medical and food industry equipment disinfectant, fabric antibacterial and deodorant finishing agent, etc. |
Risk Codes | R36/38 - Irritating to eyes and skin. R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S39 - Wear eye / face protection. S46 - If swallowed, seek medical advice immediately and show this container or label. S60 - This material and its container must be disposed of as hazardous waste. S61 - Avoid release to the environment. Refer to special instructions / safety data sheets. S24/25 - Avoid contact with skin and eyes. S22 - Do not breathe dust. S36 - Wear suitable protective clothing. |
UN IDs | UN 3077 9/PG 3 |
WGK Germany | 2 |
RTECS | KO1100000 |
TSCA | Yes |
HS Code | 29095000 |
Hazard Class | 9 |
Packing Group | III |
Toxicity | LD50 orl-rat: 3700 mg/kg 26UZAB 6,245,68/70 |
Raw Materials | 2,4-Dichlorophenol Potassium hydroxide |
Reference Show more | 1. [IF = 2.563] Zhang Huidan et al."Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in mortierella alpina. Bmc Biotechnol. 2018 Dec;18(1):1-9 2. [IF = 4.964] Shuang Bao et al." Effects of triclosan. "Aquattoxicol. 2021 Jan;230:105679 Note: part Our company can only provide part of the information, we do not guarantee the authority of the information provided, only for the reference of the customer exchange research. storage conditions: 2-8℃ solubility: slightly soluble in water, soluble in acetone, ethanol, isopropanol, propylene glycol, carbon tetrachloride and other solvents and Tween 20, tween 80 and other surfactants. Appearance: white to off-white powder Boiling Point: 344.6°C at 760 mmHg Melting Point: 56-60°C in vivo study: Triclosan plays a pathological role in promoting tissue fibrosis and hepatocarcinogenesis. It accelerates the development of liver cancer in mice, long-term effects on liver injury, fibrosis and inflammatory responses. In vitro studies: treatment of cancer cells with triclosan at physiologically relevant concentrations significantly increased the number of colonies of cancer cells. triclosan-treated cells had a mesenchymal-like cell morphology, with reduced cell-to-cell adhesion, E-cadherin reduction, and a significant increase in EMT markers, such as N-cadherin, vimentin, snail, and slug. Triclosan may enhance cancer cell viability and motility through the EMT process in the isolated state. Triclosan is a diphenyl ether derivative used as a preservative in cosmetics and soaps. It has a bacteriostatic effect. |