307926-51-8 - Names and Identifiers
Name | (1S,2S)-(+)-[1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]aluminum(III) chloride
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Synonyms | (S,S)Salen AI (S,S)-N,N-BIS(3,5-DITBUTYLSALICYLIDENE)- (s,s)-n,n'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminoaluminum chloride (s,s)-n,n'-bis(3,5-di-tert-butylsalicylidene)-1,2-cyclohexanediaminoaluminum(iii) chloride (S,S)-(+)-N,N'-Bis(3,5-di-tert-butylsalicylidene)-1,2-diaminocyclohexanealuminum(III)chloride (1S,2S)-(+)-[1,2-Cyclohexanediamino-N,N'-bis(3,5-di-t-butylsalicylidene)]aluminum(III) chloride Aluminum,chloro[[2,2'-[(1S,2S)-1,2-cyclohexanediylbis[(nitrilo-kN)methylidyne]]bis[4,6-bis(1,1-dimethylethyl)phenolato-kO]](2-)]-, (SP-5-13)- (9CI)
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CAS | 307926-51-8
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InChI | InChI=1/C36H54N2O2.Al.3ClH/c1-33(2,3)25-17-23(31(39)27(19-25)35(7,8)9)21-37-29-15-13-14-16-30(29)38-22-24-18-26(34(4,5)6)20-28(32(24)40)36(10,11)12;;;;/h17-22,29-30,39-40H,13-16H2,1-12H3;;3*1H/q;+3;;;/p-3/b37-21+,38-22+;;;;/t29-,30-;;;;/m0..../s1 |
307926-51-8 - Physico-chemical Properties
Molecular Formula | C36H52AlClN2O2
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Molar Mass | 607.254 |
Melting Point | >350°C(lit.) |
Appearance | Powder |
Color | yellow |
Storage Condition | 2-8 ℃, dark, nitrogen storage |
307926-51-8 - Risk and Safety
Hazard Symbols | Xn - Harmful
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Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
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Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
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WGK Germany | 3 |
307926-51-8 - Introduction
(1S,2S)-( )-[1,2-cyclohexanediamine-N,N'-bis(3,5-di-t-butylsalicylidene)]aluminum(III) chloride is an organoaluminum compound with the chemical formula C30H54AlClN2O2. The following is an introduction to its nature, use, formulation and safety information:
Nature:
(1S,2S)-( )-[1,2-cyclohexanediamine-N,N'-bis(3,5-di-t-butylsalicylidene)]aluminum(III) chloride is an organic aluminum salt, white to yellowish white crystalline powder. It is stable at room temperature and forms a solution when dissolved in a non-polar solvent (such as chloroform, petroleum ether, etc.). The solution of the compound has chirality, and its optical rotation degree is positive rotation. It is a sterically hindered ligand, and its conformational and chiral interactions make it an important application in chiral catalytic chemical reactions.
Use:
(1S,2S)-( )-[1,2-cyclohexanediamine-N,N'-bis(3,5-di-t-butylsalicylidene)]aluminum(III) chloride is mainly used as a chiral inducer and chiral ligand. It has a wide range of applications in the field of organic synthesis, and can be used for asymmetric catalytic reactions, such as the synthesis of asymmetric phosphites, asymmetric nucleophilic substitution reactions, etc. It can increase the stereoselectivity of the reaction, so that the product tends to form a product of a particular chirality.
Method:
The preparation method of (1S,2S)-( )-[1,2-cyclohexanediamine-N,N'-bis(3,5-di-t-butylsalicylidene)]aluminum(III) chloride is more complicated, specialized equipment and techniques are required in the laboratory. In general, it can be prepared by reacting (1S,2S)-cyclohexanediamine with 3,5-tert-butylsalicylaldehyde to give the target compound, followed by reaction with aluminum chloride.
Safety Information:
(1S,2S)-( )-[1,2-cyclohexanediamine-N,N'-bis(3,5-di-t-butylsalicylidene)]aluminum(III) chloride has high security, but it is still an organic compound and needs to be handled with caution. Avoid contact with air, humid conditions and strong oxidants during handling and storage. To avoid fire or explosion. Wear protective gloves and eye protection during use and handling. When necessary, work in a well-ventilated laboratory. In the event of accidental inhalation, ingestion or exposure to the compound, wash off immediately and seek medical help.
Last Update:2024-04-10 22:29:15