3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Names and Identifiers
Name | 3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
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Synonyms | LogP 5-Fluoropyridinyl-3-boronicacidpinacolate 3-FLUOROPYRIDINE-5-BORONIC ACID PINACOL ESTER 5-Fluoropyridin-3-ylboronic acid pinacol ester 3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) 3-Fluoro-5-(4,4,5,5-tetraMethy-[1,3,2]dioxaborolan-2-yl)pyridine 3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine 3-FLUORO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)PYRIDINE 3-Fluoro-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridine Pyridine, 3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)- 3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 2-(5-Fluoropyridin-3-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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CAS | 719268-92-5
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InChI | InChI=1/C11H15BFNO2/c1-10(2)11(3,4)16-12(15-10)8-5-9(13)7-14-6-8/h5-7H,1-4H3 |
InChIKey | VFMTUTYBMBTIGA-UHFFFAOYSA-N |
3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Physico-chemical Properties
Molecular Formula | C11H15BFNO2
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Molar Mass | 223.05 |
Density | 1.09±0.1 g/cm3(Predicted) |
Melting Point | 55.0 to 59.0 °C |
Boling Point | 294.5±25.0 °C(Predicted) |
Flash Point | 131.901°C |
Vapor Presure | 0.003mmHg at 25°C |
pKa | 2.80±0.22(Predicted) |
Storage Condition | 2-8℃ |
Sensitive | Irritant |
Refractive Index | 1.477 |
MDL | MFCD07780754 |
3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Risk and Safety
Hazard Symbols | Xi - Irritant
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WGK Germany | 3 |
Hazard Note | Irritant |
3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine - Introduction
3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is an organic compound whose chemical formula is C12H15BFNO2. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: Colorless or light yellow liquid.
-Melting point: approximately -10°C to -5°C.
-Boiling point: about 210 ℃ to 220 ℃.
-Solubility: Soluble in organic solvents such as ether, ketone, etc.
Use:
-As an intermediate in chemical synthesis, it is widely used in organic synthesis reactions.
-Can be used to prepare other boron-containing organic compounds.
Preparation Method:
The preparation of 3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is usually carried out by organic chemical synthesis methods. A common preparation method is the reaction of 3-fluoropyridine and 4,4, 5,5-tetramethyl -1,3, 2-dioxophen-2-ol with trimethylsilylchloromethane, followed by reaction with trimethylborate, and finally the target product is obtained by desilylchloromethane.
Safety Information:
- 3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine has limited toxicity information, but as a chemical, attention must be paid to safe operation. Avoid contact with skin, eyes and respiratory tract.
-Wear appropriate personal protective equipment such as chemical protective gloves, goggles, and gas masks during use.
-Store it in a sealed container, away from fire and oxidizing agents, and avoid high temperatures.
Please note that the above information is for reference only. If you need to use or handle the substance, please refer to the corresponding safety data sheet (SDS) or consult a professional for more detailed information.
Last Update:2024-04-10 22:29:15