3-Chloro-4-hydroxy-5-methoxyphenylboronicacid, pinacol ester
3-Chloro-4-hydroxy-5-methoxyphenylboronicacid, pinacol ester
CAS: 1003298-84-7
Molecular Formula: C13H18BClO4
3-Chloro-4-hydroxy-5-methoxyphenylboronicacid, pinacol ester - Names and Identifiers
3-Chloro-4-hydroxy-5-methoxyphenylboronicacid, pinacol ester - Physico-chemical Properties
| Molecular Formula | C13H18BClO4 |
| Molar Mass | 284.54 |
| Storage Condition | 2-8°C |
| Sensitive | Irritant |
| MDL | MFCD05663844 |
3-Chloro-4-hydroxy-5-methoxyphenylboronicacid, pinacol ester - Risk and Safety
| WGK Germany | 3 |
3-Chloro-4-hydroxy-5-methoxyphenylboronicacid, pinacol ester - Introduction
pinacol, also known as, pinacol ester, is an organic compound. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C14H19BClO4
-Molecular weight: 304.66g/mol
-Melting point: 180-184°C
-Boiling Point: 455.7°C at 760 mmHg
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and acetonitrile
Use:
-, pinacol ester is an important organic synthesis intermediate, commonly used in the synthesis of drugs, pesticides and organic materials.
-It is widely used in the preparation of anti-cancer drugs and other biologically active compounds in the pharmaceutical field.
Preparation Method:
-, the preparation of pinacol ester can be simplified by the synthesis steps, as follows:
1.2,6-dinitro-p-methoxybenzene was used as starting material, and 2,6-diamino-p-methoxybenzene was obtained by nitration and reduction reaction.
2. the reaction of 2,6-diamino-p-methoxybenzene and 1,3,2-dioxaborane -2-ethanolate generates 2-methoxy -4-(4,4,5,5-tetramethyl -1,3,2-dioxabororan-2-yl) phenol.
3. The obtained 2-methoxy-4-(4,4,5,5-tetramethyl -1,3, 2-dioxabororan-2-yl) phenol is reacted with a nucleophile (such as HCl or Cl2) to obtain pinacol ester.
Safety Information:
-.. pinacol the safety of ester has not been fully evaluated, please pay attention to safety protection measures during operation or use.
-Avoid inhalation, swallowing or contact with skin and eyes.
-During operation, it is recommended to wear appropriate protective equipment, such as gloves, goggles and protective clothing.
-In the event of accidental contact or ingestion, seek medical help immediately and take appropriate first aid measures as recommended by your doctor.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C14H19BClO4
-Molecular weight: 304.66g/mol
-Melting point: 180-184°C
-Boiling Point: 455.7°C at 760 mmHg
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide and acetonitrile
Use:
-, pinacol ester is an important organic synthesis intermediate, commonly used in the synthesis of drugs, pesticides and organic materials.
-It is widely used in the preparation of anti-cancer drugs and other biologically active compounds in the pharmaceutical field.
Preparation Method:
-, the preparation of pinacol ester can be simplified by the synthesis steps, as follows:
1.2,6-dinitro-p-methoxybenzene was used as starting material, and 2,6-diamino-p-methoxybenzene was obtained by nitration and reduction reaction.
2. the reaction of 2,6-diamino-p-methoxybenzene and 1,3,2-dioxaborane -2-ethanolate generates 2-methoxy -4-(4,4,5,5-tetramethyl -1,3,2-dioxabororan-2-yl) phenol.
3. The obtained 2-methoxy-4-(4,4,5,5-tetramethyl -1,3, 2-dioxabororan-2-yl) phenol is reacted with a nucleophile (such as HCl or Cl2) to obtain pinacol ester.
Safety Information:
-.. pinacol the safety of ester has not been fully evaluated, please pay attention to safety protection measures during operation or use.
-Avoid inhalation, swallowing or contact with skin and eyes.
-During operation, it is recommended to wear appropriate protective equipment, such as gloves, goggles and protective clothing.
-In the event of accidental contact or ingestion, seek medical help immediately and take appropriate first aid measures as recommended by your doctor.
Last Update：2024-04-09 15:18:10
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Product Name: 2-CHLORO-6-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Visit Supplier Webpage Request for quotationCAS: 1003298-84-7
Tel: +86-18821248368
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Spot supply
Product Name: 2-CHLORO-6-METHOXY-4-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENOL Visit Supplier Webpage Request for quotationCAS: 1003298-84-7
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
View History
3-Chloro-4-hydroxy-5-methoxyphenylboronicacid, pinacol ester
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2-甲基-β-萘并噻唑
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2-CHLORO-5-(5-[(4-CHLOROBENZYL)THIO]-4-[3-(TRIFLUOROMETHYL)PHENYL]-4H-1,2,4-TRIAZOL-3-YL)PYRIDINE
3-Formylthiophene-2-carboxylic acid methyl ester
Piston for pumps with self flush option
VINBLASTINE SULFATE(RG)
(4-methoxy-5-methyl-1-oxidopyridin-1-ium-2-yl)methanol
3-Cyclohexene-1-carboxylic acid 3-cyclohexenylmethyl ester
2-甲基-β-萘并噻唑
Carbamic acid, [(1Z)-1-(hydroxymethyl)-1-propenyl]-, 1,1-dimethylethyl ester
Phenol, 5-[4-(4-hydroxy-3-methoxyphenyl)-2,3-dimethylbutyl]-2,3-dimethoxy-, (-)-
2-CHLORO-5-(5-[(4-CHLOROBENZYL)THIO]-4-[3-(TRIFLUOROMETHYL)PHENYL]-4H-1,2,4-TRIAZOL-3-YL)PYRIDINE