3-Boc-氨基-3-(2'-Cbz-哌啶基)丙酸 - Names and Identifiers
Name | 3-(1-benzyloxycarbonyl-2-piperidyl)-3-(tert-butoxycarbonylamino)propanoic acid
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Synonyms | 3-Boc-amino-3-(2'-Cbz)piperidinepropionic acid 3-(1-benzyloxycarbonyl-2-piperidyl)-3-(tert-butoxycarbonylamino)propanoic acid 3-(1-((Benzyloxy)carbonyl)piperidin-2-yl)-3-((tert-butoxycarbonyl)amino)propanoic acid beta-[[(tert-Butoxyl)carbonyl]amino]-1-[(phenylmethoxy)carbonyl]-2-piperidinepropanoic acid 2-Piperidinepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[(phenylmethoxy)carbonyl]- 2-Piperidinepropanoic acid, .beta.-[[(1,1-dimethylethoxy)carbonyl]amino]-1-[(phenylmethoxy)carbonyl]-
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CAS | 886362-34-1
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InChI | InChI=1/C21H30N2O6/c1-21(2,3)29-19(26)22-16(13-18(24)25)17-11-7-8-12-23(17)20(27)28-14-15-9-5-4-6-10-15/h4-6,9-10,16-17H,7-8,11-14H2,1-3H3,(H,22,26)(H,24,25) |
3-Boc-氨基-3-(2'-Cbz-哌啶基)丙酸 - Physico-chemical Properties
Molecular Formula | C21H30N2O6
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Molar Mass | 406.47 |
Density | 1.204 |
Boling Point | 581.9±35.0 °C(Predicted) |
Flash Point | 305.7°C |
Vapor Presure | 2.22E-14mmHg at 25°C |
pKa | 4.44±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | 1.54 |
3-Boc-氨基-3-(2'-Cbz-哌啶基)丙酸 - Introduction
3-(+)-3-(tert-butoxycarbonylamino)propanoic acid is an organic compound whose chemical formula is C27H35N3O6.
Nature:
-Appearance: White solid
-Density: 1.23g/cm³
-Melting point: 90-92°C
-Solubility: Slightly soluble in water, soluble in some organic solvents such as methanol and dimethyl amide
Use:
3-(tert-butoxycarbonylamino)-3-propanoic acid is an intermediate in synthesis and is often used to prepare other compounds. Its amino and carboxyl groups can participate in various chemical reactions for the synthesis of drugs, natural products and other compounds.
Preparation Method:
3-(br)-3-(tert-butoxycarbonylamino)propanoic acid is prepared as follows:
1. Amino -3-(2 '-Cbz-piperidinyl) propionic acid is first dissolved in dimethylformamide.
2. The tri-tert-butoxycarbonylamino group is activated and added to the reaction system.
3. reaction reaction for several hours, control temperature at room temperature.
4. After the reaction, the pure product was obtained by freezing crystallization and filtration.
Safety Information:
3-(tert-butoxycarbonylamino)-3-propanoic acid is generally relatively safe under normal operating conditions, but the following matters still need to be paid attention:
-Use with appropriate protective equipment, such as goggles, gloves and lab coats.
-Avoid contact with skin, eyes and respiratory tract.
-Avoid eating by mistake and do not place it in an unmarked container to avoid accidents.
-When storing, please place it in a sealed container, away from fire and oxidizing agents, and store it in a cool and dry place.
Please note that for the use and storage of chemicals, please carefully read the relevant chemical safety data forms, and follow the correct operating procedures and professional advice.
Last Update:2024-04-09 15:18:00